UFGI Publication Round-Up: Week of 6/2/2025

UFGI Publication Round-Up: Week of 6/2/2025

Human Germline Genome Editing, 10 Years On.

Cwik B.

JAMA. 2025 Jun 4. doi: 10.1001/jama.2025.7654. Online ahead of print.

PMID: 40465282

 

 


Targeting METTL3 protein by proteolysis-targeting chimeras: A novel therapeutic approach for acute myeloid leukemia.

Nar R, Wu Z, Li Y, Smith A, Zhang Y, Wang J, Yu F, Gao S, Yu C, Huo Z, Zheng G, Qian Z.

Genes Dis. 2024 Nov 7;12(4):101452. doi: 10.1016/j.gendis.2024.101452. eCollection 2025 Jul.

PMID: 40453361

 

 

Epigenetic age acceleration and psychosocial stressors in early childhood.

Mulligan CJ.

Epigenomics. 2025 Jun 2:1-10. doi: 10.1080/17501911.2025.2508684. Online ahead of print.

PMID: 40454979

 

 


Global tracking of marine megafauna space use reveals how to achieve conservation targets.

Sequeira AMM, Rodríguez JP, Marley SA, Calich HJ, van der Mheen M, VanCompernolle M, Arrowsmith LM, Peel LR, Queiroz N, Vedor M, da Costa I, Mucientes G, Couto A, Humphries NE, Abalo-Morla S, Abascal FJ, Abercrombie DL, Abrantes K, Abreu-Grobois FA, Afonso AS, Afonso P, Ahonen H, Åkesson S, Alfaro-Shigueto J, Andrews RD, Angelier F, Antonopoulou M, Arata JA, Araujo G, Arauz R, Arcos JM, Arregui I, Arrizabalaga H, Auger-Méthé M, Bach S, Bailleul F, Baird RW, Balazs GH, Barco SG, Barnett A, Baverstock W, Baylis AMM, Beard A, Bécares J, Belda EJ, Bell I, Bennison A, Benson SR, Bernal D, Berumen ML, Bessudo S, Bezerra NPA, Blaison AV, Blanco GS, Block BA, Bolton M, Bond ME, Bonfil R, Braun CD, Broderick AC, Brooke ML, Brooks AML, Brooks EJ, Bruno IM, Burns JM, Byrne ME, Campana SE, Campbell HA, Campbell RA, Carlisle A, Carmichael RH, Carroll G, Casale P, Ceia FR, Chapman DD, Chapple TK, Charrassin JB, Chiaradia A, Chisholm J, Clarke CR, Clay TA, Cleguer C, Clingham E, Clua EEG, Cochran JEM, Constantine R, Cooper RW, Crochelet E, Cronin M, Cuevas E, DaCosta KP, Dagorn L, Daly R, Davis RW, de Bruyn PJN, Delgado-Trejo C, Dellinger T, Derville S, Diamant S, DiMatteo A, Dodge KL, Doherty PD, Double MC, Dove ADM, Doyle TK, Drew MJ, Dubbs LL, Duffy CAJ, Dutton PH, Edwards EWJ, Einoder LD, Erdmann MV, Espinoza E, Esteban N, Fagundes AI, Feare C, Ferguson SH, Ferreira LC, Ferretti F, Filmalter J, Finucci B, Fischer GC, Fitzpatrick RJ, Fontes J, Formia A, Fossette S, Francis MP, Friedlaender AS, Furtado M, Gallagher AJ, Garrigue C, Gennari E, Gilchrist HG, Godley BJ, Goldsworthy SD, Gollock M, Carman VG, Grecian WJ, Green JR, Guinet C, Gustafson J, Guttridge TL, Guzman HM, Hamer D, Hamer KC, Hammerschlag N, Hammill MO, Harman L, Harrison E, Hart CE, Harris AE, Hastie G, Hazin FHV, Heard M, Hearn AR, Heide-Jørgensen MP, Henry L, Henry RW 3rd, Hernandez VG, Herrera AE, Hindell MA, Holdsworth JC, Holmes BJ, Howey LA, Hoyos Padilla EM, Huckstadt LA, Hueter RE, Lara PH, Hussey NE, Huveneers C, Hyland K, Irion DT, Jacoby DMP, Jaeger A, Jaidah MY, Jessopp M, Jewell OJD, Johnson R, Jones CG, Jonsen ID, Jordan LKB, Jorgensen SJ, Kato A, Ketchum JT, Kitaysky AS, Klimley AP, Kock AA, Koen P, Archila FL, Lana FO, Lane JV, Le Corre M, Lea MA, Lea J, Leat EHK, Lee OA, Levenson JJ, Ley-Quiñonez CP, Llewellyn F, Lockhart G, Lopez GG, Mendilaharsu ML, Lowther AD, Luschi P, Lutcavage ME, Lyon WS, Macena BCL, Mackay AI, Madden CA, Mallory ML, Mangel JC, Manning M, Mansfield KL, March D, Marco A, Marcoux M, Acuña-Marrero D, Marsh H, Marshall H, Mate B, McAllister JD, McGuire RL, McKenzie J, McLeay L, McMahon CR, Modest M, Morris J, Muelbert MMC, Namboothri N, Nichols WJ, Nicoll MAC, Norman BM, Norris K, Olsen E, Oppel S, Orlowski S, Pagano AM, Page B, Paiva VH, Palacios DM, Papastamatiou YP, Parker DM, Pattiaratchi C, Peckham H, Peñaherrera-Palma CR, Pepperell JG, Phillips RA, Pierce SJ, Pikesley SK, Pilcher NJ, Pinet P, Pinkerton M, Pirotta E, Plot V, Powell AN, Powers KD, Prebble CEM, Preston TJ, Prieto R, Prosdocimi L, Quinn JL, Quintero LM, Raclot T, Ramirez I, Ramírez-Macías D, Ramos JA, Read AJ, Ream R, Rees AF, Reina RD, Reisinger RR, Revuelta O, Reynolds SD, Richardson AJ, Riekkola L, Riet-Sapriza FG, Robinson DP, Robinson PW, Rocha CFD, Rogers TL, Rohner CA, Ropert-Coudert Y, Ross M, Rowat DRL, Ruhomaun K, Sagar PM, Samoilys MA, Sanchez S, Sandoval-Lugo AG, Dos Santos EAP, Santos AM, Scales KL, Schofield G, Semmens JM, Setyawan E, Shaffer SA, Shanker K, Sheaves M, Shillinger GL, Shivji MS, Sianipar A, Silk JRD, Silva MA, Sim J, Simpson SJ, Skomal G, Slip DJ, Smale MJ, Soler GA, Soria M, Sousa LL, Southall EJ, Stahl JC, Stehfest KM, Sterling JT, Stevens JD, Stevens GMW, Stewart JD, Swaminathan A, Takahashi A, Tatayah V, Thiebot JB, Thompson PM, Thorrold SR, Thums M, Tomás J, Torres LG, Towner A, Trathan PN, Tyminski JP, Sagarminaga van Buiten R, Van Dam RP, Vandeperre F, Varo-Cruz N, Vaudo JJ, Vely M, Villegas-Amtmann S, Vincent C, Waayers D, Wanless S, Watanabe YY, Watt CA, Weber SB, Weber N, Weise MJ, Welch L, Wells RS, Werry JM, Wetherbee BM, White TD, Whiting SD, Whiting AU, Wiebkin A, Wienecke B, Wildermann NE, Wiley DN, Will A, Williams S, Windstein M, Wischnewski S, Witt MJ, Womersley FC, Wood AG, Wright LJ, Xavier JC, Yamamoto T, Yurkowski DJ, Zarate PM, Zavala-Norzagaray A, Zerbini AN, Costa DP, Harcourt R, Meekan MG, Hays GC, Sims DW, Duarte CM, Eguíluz VM.

Science. 2025 Jun 5;388(6751):1086-1097. doi: 10.1126/science.adl0239. Epub 2025 Jun 5.

PMID: 40472106

 

 

AnimalMotionViz: An interactive software tool for tracking and visualizing animal motion patterns using computer vision.

De Castro AL, Wang J, Bonney-King JG, Morota G, Miller-Cushon EK, Yu H.

JDS Commun. 2025 Mar 3;6(3):416-421. doi: 10.3168/jdsc.2024-0706. eCollection 2025 May.

PMID: 40458158

 

 


Comparison of combined intravenous and intra-arterial thrombolysis with intravenous thrombolysis alone in stroke patients undergoing mechanical thrombectomy: a propensity-matched analysis.

Elawady SS, Abo Kasem R, Mulpur B, Cunningham C, Matsukawa H, Sowlat MM, Orscelik A, Nawabi NLA, Isidor J, Maier I, Jabbour P, Kim JT, Wolfe SQ, Rai A, Starke RM, Psychogios MN, Samaniego EA, Yoshimura S, Cuellar H, Howard BM, Alawieh A, Alaraj A, Ezzeldin M, Romano DG, Tanweer O, Mascitelli JR, Fragata I, Polifka AJ, Siddiqui F, Osbun JW, Grandhi R, Crosa RJ, Matouk C, Park MS, Brinjikji W, Moss M, Daglioglu E, Williamson R, Navia P, Kan P, De Leacy RA, Chowdhry SA, Altschul D, Spiotta AM, Levitt MR, Goyal N.

J Neurointerv Surg. 2025 Jun 1;17(e2):e261-e268. doi: 10.1136/jnis-2024-021975.

PMID: 39179373

 

 


Mechanical thrombectomy in elderly stroke patients with low ASPECTS: insights from STAR.

Cunningham C, Hubbard Z, Abo Kasem R, Elawady SS, Sowlat MM, Matsukawa H, Maier I, Jabbour P, Kim JT, Wolfe SQ, Rai AT, Starke RM, Psychogios MN, Samaniego EA, Goyal N, Yoshimura S, Cuellar H, Howard BM, Alawieh A, Alaraj A, Ezzeldin M, Romano DG, Tanweer O, Mascitelli JR, Fragata I, Polifka AJ, Siddiqui F, Osbun JW, Grandhi R, Crosa RJ, Matouk C, Park MS, Levitt MR, Brinjikji W, Moss M, Daglioglu E, Williamson R, Navia P, Kan P, De Leacy RA, Chowdhry SA, Altschul D, Al Kasab S, Spiotta AM.

J Neurointerv Surg. 2025 Jun 1;17(e2):e206-e215. doi: 10.1136/jnis-2024-022677.

PMID: 39855673

 

 

Metagenome-based microbial metabolic strategies to mitigate ruminal methane emissions using Komagataeibacter-based symbiotics.

Kang MG, Kwak MJ, Kang A, Park J, Lee DJ, Mun J, Kim S, Mun D, Lee W, Choi H, Seo E, Choi Y, Jeong KC, Oh S, Kim J, Kim Y.

Sci Total Environ. 2025 Jun 2;987:179793. doi: 10.1016/j.scitotenv.2025.179793. Online ahead of print.

PMID: 40460541

 

 

Force control deficits in rapid eye movement behavior disorder and Parkinson’s disease.

Tobin ER, Delmas S, Kim JJ, Hubbard JC, Yacoubi B, Lou X, Presti MF, Kraus A, Berry RB, Jaffee MS, Christou EA, Vaillancourt DE.

Clin Neurophysiol. 2025 May 25;176:2110763. doi: 10.1016/j.clinph.2025.2110763. Online ahead of print.

PMID: 40472441

 

 


Maize big embryo 6 reveals roles of plastidial and cytosolic prephenate aminotransferases in seed and plant development.

Liu H, El-Azaz J, Yobi A, Yokoyama R, Wu S, Chin-Quee AD, Gorman Z, Angelovici R, Block AK, Maeda HA, McCarty DR, Suzuki M.

Plant Cell. 2025 Jun 4;37(6):koaf067. doi: 10.1093/plcell/koaf067.

PMID: 40476681

 

 


Gaps and strategies for accurate simulation of waterlogging impacts on crop productivity.

Garcia-Vila M, Dos Santos Vianna M, Harrison MT, Liu K, de S Nóia-Júnior R, Weber TKD, Zhao J, Acutis M, Archontoulis S, Asseng S, Aubry P, Balkovic J, Basso B, Chen X, Chen Y, de Jong van Lier Q, Delandmeter M, de Wit A, Dumont B, Ferrise R, Folberth C, Gabbrielli M, Gaiser T, Gorooei A, Hoogenboom G, Kersebaum KC, Kim YU, Kraus D, Liu B, Martin L, Metselaar K, Nendel C, Padovan G, Perego A, Seserman DM, Scheer C, Shelia V, Stocca V, Tao F, Wang E, Webber H, Zhao Z, Zhu Y, Palosuo T.

Nat Food. 2025 Jun 6. doi: 10.1038/s43016-025-01179-y. Online ahead of print.

PMID: 40481339

 

 

A phase 1 clinical trial shows safe, sustained, AAV-mediated expression of IL-1Ra in the human osteoarthritic knee joint.

De la Vega RE, Sellon JL, Smith J, Wisniewski SJ, Jurisson ML, Frick MA, Scrabeck TL, Block JB, Mills CJ, Pohlkamp ZW, Coenen MJ, Hawse GP, Abdul TY, Conaghan P, Keravala A, Chalberg TW, Robbins PD, Ghivizzani SC, Evans CH.

Sci Transl Med. 2025 Jun 4;17(801):eadu9804. doi: 10.1126/scitranslmed.adu9804. Epub 2025 Jun 4.

PMID: 40465688

 

 


A hundred species, mostly new-first assessment of ribbon worm diversity and distribution in Oman.

Maslakova S, Cherneva I, Kahn E, Wong A, Paulay G.

PeerJ. 2025 May 28;13:e19438. doi: 10.7717/peerj.19438. eCollection 2025.

PMID: 40452930

 

 

Increased inflammation as well as decreased endoplasmic reticulum stress and translation differentiate pancreatic islets from donors with pre-symptomatic stage 1 type 1 diabetes and non-diabetic donors.

Swensen AC, Piehowski PD, Chen J, Chan XY, Kelly SS, Petyuk VA, Moore RJ, Nasif L, Butterworth EA, Atkinson MA, Kulkarni RN, Campbell-Thompson M, Mathews CE, Qian WJ.

Diabetologia. 2025 Jun 2. doi: 10.1007/s00125-025-06417-3. Online ahead of print.

PMID: 40457096

 

 


Etiologic Determinants and Characteristics of Diabetes in Haitian Youth (EDDHY Study).

Jean-Baptiste E, Larco P, Oettingen JEV, Noble JA, Mack SJ, Song N, Martin HRN, Rozemuller E, Atkinson MA, Govender D, Larco NC, Ogle GD.

Pediatr Diabetes. 2025 May 25;2025:9974561. doi: 10.1155/pedi/9974561. eCollection 2025.

PMID: 40458319

 

 

Development of a Pharmacogenomics Case Repository for Pharmacy Educators.

Cropp CD, Gálvez-Peralta M, Ham AL, Hoger JD, Ward KM, Norris M, Petry NJ, Roosan MR, Donnelly RS, Kinney S, Brazeau D, Berenbrok LA, Farrell CL, Lee YM, Iwuchukwu OF, Kisor DF, Cicali EJ.

Am J Pharm Educ. 2025 Jun;89(6):101397. doi: 10.1016/j.ajpe.2025.101397. Epub 2025 Apr 1.

PMID: 40180241

 

 

Hierarchical Extended Linkage Method (HELM)’s Deep Dive into Hybrid Clustering Strategies.

Chen L, Brylle Woody Santos J, Gaza J, Perez A, Miranda-Quintana RA.

J Chem Inf Model. 2025 Jun 2. doi: 10.1021/acs.jcim.5c00539. Online ahead of print.

PMID: 40452401

 

 


Translation suppresses exogenous target RNA-mediated microRNA decay.

Li T, Li L, Hiers NM, Sheng P, Wang Y, Traugot CM, Effinger-Morris JF, Akaphan P, Liu Y, Bian J, Fujii K, Xie M.

Nat Commun. 2025 Jun 6;16(1):5257. doi: 10.1038/s41467-025-60374-4.

PMID: 40480978

 

 

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.

Leibold P, Lteif C, Duarte JD.

Front Genet. 2025 May 20;16:1490863. doi: 10.3389/fgene.2025.1490863. eCollection 2025.

PMID: 40463714

 

 

Translation suppresses exogenous target RNA-mediated microRNA decay.

Li T, Li L, Hiers NM, Sheng P, Wang Y, Traugot CM, Effinger-Morris JF, Akaphan P, Liu Y, Bian J, Fujii K, Xie M.

Nat Commun. 2025 Jun 6;16(1):5257. doi: 10.1038/s41467-025-60374-4.

PMID: 40480978

 

 


A viral circular RNA in Kaposi’s sarcoma-associated herpesvirus modulates viral and host gene expression during latent and lytic replication.

Torres S, Jain V, Stribling D, Gay LA, Naeem M, Baddoo M, Flemington EK, Tibbetts SA, Renne R.

Explor Target Antitumor Ther. 2025 May 29;6:1002320. doi: 10.37349/etat.2025.1002320. eCollection 2025.

PMID: 40452889

 

 

Multiplex digital spatial profiling identifies subregion dependent targeted proteome changes across variants of dementia.

Bolen ML, Menees KB, Gearing M, Gong J, Ren Y, Merchak AR, Murray ME, McEachin ZT, Tansey MG.

NPJ Dement. 2025;1(1):10. doi: 10.1038/s44400-025-00010-6. Epub 2025 Jun 3.

PMID: 40476255

 

 


Spiny mice (Acomys) regenerate wounded whisker pad skin with whisker follicles, muscles, and targeted innervation.

Varholick JA, Kondapaneni R, Maden M.

NPJ Regen Med. 2025 Jun 4;10(1):28. doi: 10.1038/s41536-025-00415-0.

PMID: 40467647

 

 


Feeding rumen-protected choline to prepartum Holstein cows in negative energy balance increases circulating lipoprotein phosphatidylcholine and triglyceride concentrations.

Myers WA, Zenobi MG, Reyes DC, Santos JEP, Staples CR, McFadden JW.

JDS Commun. 2025 Mar 3;6(3):304-308. doi: 10.3168/jdsc.2024-0661. eCollection 2025 May.

PMID: 40458167

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