UFGI Publication Round-Up: 9/21/2026

Tian T, Xue Y, Sun C, Yang L, Wang J, Jin-Smith B, Barkin JM, Nzegwu M, Jia L, Zhou H, Khambu B, Yin XM, Zhou D, Chambers AG, Fu D, Lin Z, Yan S, Wu L, Petersen B, Li C, Zuo L, Duarte S, Zarrinpar A, Wang H, Pi L.

Nat Commun. 2026 Aug 22;17(1):10047. doi: 10.1038/s41467-026-77089-9.

PMID: 42768043

DNL343 and Disease Progression in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.

Paganoni S, Chibnik LB, Quintana M, Macklin EA, Detry MA, Vestrucci M, Paulon G, McGlothlin A, Wang J, Walk D, Elman L, Chase M, Heyd L, Harkey B, Sherman AV, Shefner J, Berry JD, Scirocco E, Giacomelli E, Yu H, Kittle G, Hall M, Ho D, Jawdat O, Ladha S, Locatelli E, Rivner M, Felice K, Katz J, Ajroud-Driss S, Fee D, Miller T, Rosow L, Quick A, Heitzman D, Foster LA, Maragakis NJ, Goutman SA, Rosenfeld J, Benatar M, Swenson A, Connors RD, Shroff S, Bedlack R, McIlduff CE, Chen IA, Fernandes JAM, Walsh A, Peltier A, Ilieva H, Diaz F, Kushlaf H, Beydoun SR, Myers B, Arcila-Londono X, Heiman-Patterson T, Elliott M, Whitesell J, Al-Lahham T, Elliott M, Olney N, Baer M, Jackson C, Young E, Caress J, Weiss MD, Kuenzler R, Nayar S, Kasarskis EJ, Simmons Z, Gibson S, Owegi MA, Goyal NA, Wymer JP, Gwathmey KG, Erickson A, Gursoy N, Alameda G, Bodkin C, Wu A, Martinez-Thompson J, Twydell PT, Andrews J, Bayat E, Rezania K, Usman U, McCluskey L, Kovvuru S, Jennings D, Garza-Meilandt A, Maciuca R, Cohen IV, Tamuly D, Eren E, Cudkowicz ME, Babu S; HEALEY ALS Platform Trial Study Group.

JAMA Netw Open. 2026 Sep 1;9(9):e2634809. doi: 10.1001/jamanetworkopen.2026.34809.

PMID: 42771346

Reply to Doyle: Emphasizing independent gene duplications and convergent molecular function.

Finegan C, Kates HR, Guralnick RP, Soltis PS, Resende MFR Jr, Ané JM, Kirst M, Folk RA, Soltis DE.

Proc Natl Acad Sci U S A. 2026 Sep 29;123(39):e2537948123. doi: 10.1073/pnas.2537948123. Epub 2026 Sep 21.

PMID: 42766736

Androgens Drive SOX9 Upregulation in Injured Proximal Tubular Cells.

Allison CV, Patel PS, Xuanyuan Q, Stayton A, Mondal M, Silvaroli JA, Karel IZ, Thorson VC, Sloane G, Thailammanal HJ, Scindia Y, Coss CC, Zepeda-Orozco D, Rao R, Bolisetty S, Mallipattu SK, Humphreys BD, Bajwa A, Pabla NS, Kim J.

Kidney Int. 2026 Sep 21:S0085-2538(26)00791-X. doi: 10.1016/j.kint.2026.07.038. Online ahead of print.

PMID: 42767609

Distinct clinical patterns of preterm infants vulnerable to intestinal injury identified by unsupervised clustering.

Oh SH, Choi YS, Chung SH, Ahn J, Kim JY, Lee EH, Aghaeepour N, Stevenson D, Neu J.

Pediatr Res. 2026 Sep 23. doi: 10.1038/s41390-026-05494-3. Online ahead of print.

PMID: 42773236

Lipopolysaccharide induces a delayed iron-handling transcript pattern in primary bovine macrophages.

Hall K, Dunston L, Lee D, Kim JH, Harvey JW, de Souza C.

Am J Vet Res. 2026 Sep 23:1-8. doi: 10.2460/ajvr.26.07.0324. Online ahead of print.

PMID: 42777765

Responses to Nei-Xiao-Luo-Li-San in Toledo Diffuse Large B-Cell Lymphoma Cells: Potential Involvement of ATF5- and HDAC-Associated Epigenetic Changes.

Zou K, Kim JH, Arunasalam S, Yangari B, Shiau DS.

Biomedicines. 2026 Sep 12;14(9):2052. doi: 10.3390/biomedicines14092052.

PMID: 42792793

Molgramostim improves exercise distance and duration in autoimmune pulmonary alveolar proteinosis: exploratory IMPALA-2 trial data.

McCarthy C, Bonella F, Inoue Y, Trapnell BC, Wang T, Ataya A, Arena R, Robinson B, Fleming R, Pratt R, Wasfi Y.

Ann Am Thorac Soc. 2026 Sep 22:aaoag301. doi: 10.1093/annalsats/aaoag301. Online ahead of print.

PMID: 42770839

Pulmonary Arterial Hypertension in Octogenarians: The Pulmonary Hypertension Association Registry.

Reddy R, Moutchia J, Ravichandran A, Runo J, Badesch DB, Moss J, Burger C, De Marco T, Horn E, Ataya A, Bryant A, Al-Naamani N, Kawut SM; PHAR Investigators.

Pulm Circ. 2026 Sep 22;16(3):e70387. doi: 10.1002/pul2.70387. eCollection 2026 Jul.

PMID: 42775130

Pancreatic Cancer Disrupts Circadian Patterns of Gene Expression in Cardiorespiratory Muscles.

Ducharme JB, Schonk MM, Gutierrez-Monreal MA, Ferreira LF, Esser KA, Judge AR, Judge SM.

J Cachexia Sarcopenia Muscle. 2026 Oct;17(5):e70383. doi: 10.1002/jcsm.70383.

PMID: 42773975

An Integrative Toxicological Assessment of the Herbicide Tebuthiuron: Elucidating Biochemical and Behavioral Responses in Developing Zebrafish.

Ferreira G, Sultan A, Kirgiz FC, Gutierrez JC, López González EC, Martyniuk CJ.

J Xenobiot. 2026 Sep 3;16(5):166. doi: 10.3390/jox16050166.

PMID: 42783609

Associative Emotional Learning in Convolutional Neural Networks.

Leem S, Keil A, Ding M, Fang R.

Neural Comput. 2026 Sep 22:1-28. doi: 10.1162/NECO.a.1580. Online ahead of print.

PMID: 42771698

ThiN as a versatile domain of transcriptional repressors and catalytic enzymes of thiamine biosynthesis in archaea.

Cox N, Weber KR, Maupin-Furlow JA.

Methods Enzymol. 2026;735:149-187. doi: 10.1016/bs.mie.2026.05.039. Epub 2026 Jun 18.

PMID: 42778270

Development of machine learning-based multi-task quantitative structure-activity relationship models for predicting toxicities in six human organ systems.

Wu PY, Chou WC, Kamineni VN, Chen CY, Hsieh JH, Vulpe CD, Lin Z.

Comput Toxicol. 2026 Mar;37:100399. doi: 10.1016/j.comtox.2025.100399. Epub 2025 Dec 24.

PMID: 42781128

Exercise training reshapes motor planning and preparation networks in cervical dystonia.

Adury RZ, Arpin DJ, Remz M, Rawls A, Vaillancourt DE, Wagle Shukla AA.

Brain. 2026 Sep 21:awag327. doi: 10.1093/brain/awag327. Online ahead of print.

PMID: 42766817

Beyond Pain: A Pilot Study of Neurodegenerative and Mitochondrial Pathway Alterations in Sickle Cell Disease Using Platelet Proteomics.

Powell-Roach K, Ogu UO, Culp E, Gupta K, Lance EI, Cao X, Leo MD, Johnson D, Kakhniashvili D, Cruz-Almeida Y, Wallace MR, Wilkie DJ, Goodman SR.

Med Sci (Basel). 2026 Aug 26;14(5):517. doi: 10.3390/medsci14050517.

PMID: 42783390

Protective IFIH1 variant reduces islet stress and dysfunction in a type 1 diabetes genetic background.

Veronese-Paniagua DA, Banks C, Bradley K, Mukherjee N, Gale SE, Hinshaw KE, Meacham AM, Iwaloye OF, Tse HM, Mathews CE, Millman JR.

iScience. 2026 Sep 17;29(10):117560. doi: 10.1016/j.isci.2026.117560. eCollection 2026 Oct 16.

PMID: 42787837

A Comprehensive Review of Bacterial Leaf Spot (Xanthomonas spp.) Host Resistance in Pepper (Capsicum spp.).

Jain M, Jaganathan D, Dutta B, Sharma A, Jones JB, Rathinasabapathi B, Nankar A.

Plant Dis. 2026 Sep 21. doi: 10.1094/PDIS-05-26-0927-FE. Online ahead of print.

PMID: 42766675

Sorbitol dehydrogenase aids grain-fill and integrates carbohydrate metabolism with redox in the hypoxic maize endosperm.

Mourad N, Rolletschek H, Langer M, Sanclemente MA, Saint-Fleur M, Herndon L, Wu S, Morais de Sousa Tinôco S, Guan J, Koch KE.

Plant Cell. 2026 Sep 21:koag293. doi: 10.1093/plcell/koag293. Online ahead of print.

PMID: 42766809