UFGI Publication Round-Up: Week of 4/21/2025

Development of an Ancestrally Inclusive Preemptive Pharmacogenetic Testing Panel.

Lteif C, Gawronski BE, Cicali EJ, Martinez KA, Newsom KJ, Starostik P, Cavallari LH, Duarte JD.

Clin Transl Sci. 2025 May;18(5):e70230. doi: 10.1111/cts.70230.

PMID: 40279185

 

 

Artificial Intelligence and Machine Learning in Cardiothoracic Surgery: Future Prospects and Ethical Issues.

Rashidi P, Kilic A, Kline A, Liu T, McCarthy PM, Johnston DR, Sade RM.

J Thorac Cardiovasc Surg. 2025 Apr 23:S0022-5223(25)00329-0. doi: 10.1016/j.jtcvs.2025.04.029. Online ahead of print.

PMID: 40280540

 

 

Lipoxin A₄/FPR2 Signaling Mitigates Ferroptosis of Alveolar Epithelial Cells via NRF2-Dependent Pathway During Lung Ischemia-Reperfusion Injury.

Kollareth DJM, Leroy V, Tu Z, Woolet-Stockton MJ, Kamat M, Garrett TJ, Atkinson C, Cai G, Upchurch GR Jr, Sharma AK.

FASEB J. 2025 Apr 30;39(8):e70545. doi: 10.1096/fj.202401475R.

PMID: 40270323

 

 

Distribution of non-falciparum malaria among symptomatic malaria patients in Dschang, West Region of Cameroon.

Tchuenkam PVK, White SJ, Potlapalli V, Keming EM, Muller MS, Kaunda DBN, Kharabora O, Dinglasan RR, Parr JB, Tume CB, Lin JT, Juliano JJ, Ali IM.

medRxiv [Preprint]. 2025 Mar 25:2025.03.24.25324523. doi: 10.1101/2025.03.24.25324523.

PMID: 40196244

 

 

Continuous glucose monitor metrics from five studies identify participants at risk for type 1 diabetes development.

Calhoun P, Spanbauer C, Steck AK, Frohnert BI, Herman MA, Keymeulen B, Veijola R, Toppari J, Desouter A, Gorus F, Atkinson M, Wilson DM, Pietropaolo S, Beck RW.

Diabetologia. 2025 May;68(5):930-939. doi: 10.1007/s00125-025-06362-1. Epub 2025 Feb 11.

PMID: 39934369

 

 

Integrated histopathology of the human pancreas throughout stages of type 1 diabetes progression.

van der Heide V, McArdle S, Nelson MS, Cerosaletti K, Gnjatic S, Mikulski Z, Posgai AL, Kusmartseva I, Atkinson M, Homann D.

bioRxiv [Preprint]. 2025 Mar 19:2025.03.18.644000. doi: 10.1101/2025.03.18.644000.

PMID: 40166299

 

 

The Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D): An NIDDK Initiative to Advance Understanding of Mechanisms Underlying Cardiovascular Disease in Type 1 Versus Type 2 Diabetes.

Jones TLZ, Kusmartseva I, Litovsky S, Thakar R, Posgai AL, Eckel RH, Atkinson MA.

Diabetes. 2025 Apr 24:db250017. doi: 10.2337/db25-0017. Online ahead of print.

PMID: 40272262

 

 

Closing the Gap Between Vision and Victory in Type 1 Diabetes: The NIDDK Human Islet Research Network (HIRN) Initiative.

Parent AV, Agarwal A, Alvarez-Dominguez JR, Arrojo E Drigo R, Atkinson MA, Brehm MA, Ferreira LMR, Kaestner KH, Kravets V, Niland JC, O’Meally D, Rouse L, Russ HA, Stabler CL, Kaddis JS.

Diabetes. 2025 Apr 24:db250097. doi: 10.2337/db25-0097. Online ahead of print.

PMID: 40272263

 

 

MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson’s HLA locus exhibits epigenetic regulation.

Kline EM, Jernigan JE, Scharer CD, Maurer J, Hicks SL, Herrick MK, Wallings RL, Kelly SD, Chang J, Menees KB, McFarland NR, Boss JM, Tansey MG, Joers V.

Sci Rep. 2025 Apr 21;15(1):13705. doi: 10.1038/s41598-025-95679-3.

PMID: 40258905

 

 

Spatiotemporal dynamics of coastal dead zones in the Gulf of Mexico over 20 years using remote sensing.

Li Y, Xia Z, Nguyen L, Wan HY, Wan L, Wang M, Jia N, Matli VRR, Li Y, Seeley M, Moran EF, Liu J.

Sci Total Environ. 2025 Apr 23;979:179461. doi: 10.1016/j.scitotenv.2025.179461. Online ahead of print.

PMID: 40280098

 

 

Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes.

Sznajder ŁJ, Khan M, Ciesiołka A, Tadross M, Nutter CA, Taylor K, Pearson CE, Lewis MH, Hines RM, Swanson MS, Sobczak K, Yuen RKC.

Nat Neurosci. 2025 Apr 21. doi: 10.1038/s41593-025-01943-0. Online ahead of print.

PMID: 40259070

 

 

Yolo-pest: an optimized YoloV8x for detection of small insect pests using smart traps.

Hakim A, Srivastava AK, Hamza A, Owais M, Habib-Ur-Rahman M, Qadri S, Qayyum MA, Ahmad Khan FZ, Mahmood MT, Gaiser T.

Sci Rep. 2025 Apr 23;15(1):14029. doi: 10.1038/s41598-025-97825-3.

PMID: 40269001

 

 

antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation.

Blin K, Shaw S, Vader L, Szenei J, Reitz ZL, Augustijn HE, Cediel-Becerra JDD, de Crécy-Lagard V, Koetsier RA, Williams SE, Cruz-Morales P, Wongwas S, Segurado Luchsinger AE, Biermann F, Korenskaia A, Zdouc MM, Meijer D, Terlouw BR, van der Hooft JJJ, Ziemert N, Helfrich EJN, Masschelein J, Corre C, Chevrette MG, van Wezel GP, Medema MH, Weber T.

Nucleic Acids Res. 2025 Apr 25:gkaf334. doi: 10.1093/nar/gkaf334. Online ahead of print.

PMID: 40276974

 

 

Nonnative tree invaders lead to declines in native tree species richness.

Liu Y, Scheiner SM, Hogan JA, Thomas MB, Soltis PS, Guralnick RP, Soltis DE, Lichstein JW.

Proc Natl Acad Sci U S A. 2025 Apr 29;122(17):e2424908122. doi: 10.1073/pnas.2424908122. Epub 2025 Apr 21.

PMID: 40258149

 

 

Sorptive removal of neonicotinoid pesticides by nanobiochars: Efficiency, kinetics, and reusability.

Radwan IM, Wang C, Kim JH, Wei H, Wang D.

J Hazard Mater. 2025 Apr 21;493:138354. doi: 10.1016/j.jhazmat.2025.138354. Online ahead of print.

PMID: 40280060

 

 

Advancing Chrononutrition for Cardiometabolic Health: A 2023 National Heart, Lung, and Blood Institute Workshop Report.

Dashti HS, Jansen EC, Zuraikat FM, Dixit S, Brown M, Laposky A, Broussard JL, Butler MP, Creasy SA, Crispim CA, Depner CM, Esser KA, Garaulet M, Hanlon EC, Makarem N, Manoogian ENC, Peterson CM, Scheer FAJL, Wright KP Jr, Goff DC Jr, Pratt CA, Gamble KL, St-Onge MP.

J Am Heart Assoc. 2025 Apr 23:e039373. doi: 10.1161/JAHA.124.039373. Online ahead of print.

PMID: 40265587

 

 

CD33-D2 isoform characterization for advancement of its therapeutic potential.

Shastri VM, Madabushi SS, Hui SK, Lamba JK.

Immunotherapy. 2025 Apr 24:1-8. doi: 10.1080/1750743X.2025.2493038. Online ahead of print.

PMID: 40272002

 

 

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM.

Cornely OA, Sprute R, Bassetti M, Chen SC, Groll AH, Kurzai O, Lass-Flörl C, Ostrosky-Zeichner L, Rautemaa-Richardson R, Revathi G, Santolaya ME, White PL, Alastruey-Izquierdo A, Arendrup MC, Baddley J, Barac A, Ben-Ami R, Brink AJ, Grothe JH, Guinea J, Hagen F, Hochhegger B, Hoenigl M, Husain S, Jabeen K, Jensen HE, Kanj SS, Koehler P, Lehrnbecher T, Lewis RE, Meis JF, Nguyen MH, Pana ZD, Rath PM, Reinhold I, Seidel D, Takazono T, Vinh DC, Zhang SX, Afeltra J, Al-Hatmi AMS, Arastehfar A, Arikan-Akdagli S, Bongomin F, Carlesse F, Chayakulkeeree M, Chai LYA, Chamani-Tabriz L, Chiller T, Chowdhary A, Clancy CJ, Colombo AL, Cortegiani A, Corzo Leon DE, Drgona L, Dudakova A, Farooqi J, Gago S, Ilkit M, Jenks JD, Klimko N, Krause R, Kumar A, Lagrou K, Lionakis MS, Lmimouni BE, Mansour MK, Meletiadis J, Mellinghoff SC, Mer M, Mikulska M, Montravers P, Neoh CF, Ozenci V, Pagano L, Pappas P, Patterson TF, Puerta-Alcalde P, Rahimli L, Rahn S, Roilides E, Rotstein C, Ruegamer T, Sabino R, Salmanton-García J, Schwartz IS, Segal E, Sidharthan N, Singhal T, Sinko J, Soman R, Spec A, Steinmann J, Stemler J, Taj-Aldeen SJ, Talento AF, Thompson GR 3rd, Toebben C, Villanueva-Lozano H, Wahyuningsih R, Weinbergerová B, Wiederhold N, Willinger B, Woo PCY, Zhu LP.

Lancet Infect Dis. 2025 May;25(5):e280-e293. doi: 10.1016/S1473-3099(24)00749-7. Epub 2025 Feb 13.

PMID: 39956121

 

 

ANI-1xBB: An ANI-Based Reactive Potential for Small Organic Molecules.

Zhang S, Zubatyuk R, Yang Y, Roitberg A, Isayev O.

J Chem Theory Comput. 2025 Apr 24. doi: 10.1021/acs.jctc.5c00347. Online ahead of print.

PMID: 40270239

 

 

Minute-scale dynamics of recurrent dike intrusions in Iceland with fiber-optic geodesy.

Li J, Biondi E, Heimisson ER, Puel S, Zhai Q, Zhang S, Hjörleifsdóttir V, Wei X, Bird E, Klesh A, Kamalov V, Gunnarsson T, Geirsson H, Zhan Z.

Science. 2025 Apr 24:eadu0225. doi: 10.1126/science.adu0225. Online ahead of print.

PMID: 40273283

 

 

 

Investigating Plasmids Diversity in X. euvesicatoria pv. perforans Population.

Kaur A, Sunny A, Jones JB, Goss EM.

Phytopathology. 2025 Apr 25. doi: 10.1094/PHYTO-02-25-0042-FI. Online ahead of print.

PMID: 40280885

 

 

High rate of mutation and efficient removal by selection of structural variants from natural populations of Caenorhabditis elegans.

Saxena AS, Baer CF.

bioRxiv [Preprint]. 2025 Mar 25:2025.03.22.644739. doi: 10.1101/2025.03.22.644739.

PMID: 40196536

 

 

Development of radioligand binding assays for REV-ERBα and REV-ERBβ.

Koelblen T, Burris EP, Burris TP.

Anal Biochem. 2025 Jul;702:115858. doi: 10.1016/j.ab.2025.115858. Epub 2025 Apr 4.

PMID: 40189177

 

 

Minding the Research Mentorship Gap During Psychiatry Residency.

Shu AH, Mathews CA, Voglmaier SM, Hirschtritt ME.

Acad Psychiatry. 2025 Apr 25. doi: 10.1007/s40596-025-02144-4. Online ahead of print.

PMID: 40281375

 

 

Atypical Postural Control Variability and Coordination Persist Into Middle and Older Adulthood in Autism Spectrum Disorder.

Qu H, Wang J, Shirley DJ, Gemmell HM, Christensen D, Orlando AM, Romero RA, Zielinski BA, Wang Z.

Autism Res. 2025 Apr;18(4):752-764. doi: 10.1002/aur.70024. Epub 2025 Mar 18.

PMID: 40103348

 

 

Design of anti-depressant phosphodiester amino acidic Keap1-Nrf2 protein-protein interaction inhibitors.

Sun Y, Wang J, Ding W, Qin Q, Wang R, Yu R, Yan J, Hou R, Liu G, Cai X, Qu Z, Zhang W, Yu J, Xing C, Zhuang C.

Redox Biol. 2025 May;82:103620. doi: 10.1016/j.redox.2025.103620. Epub 2025 Mar 26.

PMID: 40174476

 

 

Nick sealing of polβ mismatch insertion products by LIG1 and LIG3α during 8-oxoG bypass leads to mutagenic or error-free base excision repair.

Lee KM, Castro E, Ratcliffe J, Lerner C, Çağlayan M.

J Biol Chem. 2025 Apr 24:108540. doi: 10.1016/j.jbc.2025.108540. Online ahead of print.

PMID: 40286853

 

 

Lipidomic Markers of Processed Meat and Unprocessed Red Meat Intake and Risk of Diabetes in American Indians.

Wen X, Miao G, Fretts AM, Chen M, Zhang Y, Umans JG, Cole SA, Best LG, Fiehn O, Zhao J.

Diabetes Care. 2025 Apr 23:dc242828. doi: 10.2337/dc24-2828. Online ahead of print.

PMID: 40267348

 

 

Identifying a Sepsis Subphenotype Characterized by Dysregulated Lipoprotein Metabolism Using a Simplified Clinical Data Algorithm.

Labilloy G, Tanaka S, Black LP, Augustin B, Hopson C, Bethencourt J, Wu D, Sulaiman D, Bertrand A, Salomão R, Graim K, Datta S, Reddy S, Guirgis FW, Hofmaenner DA.

Shock. 2025 Apr 23. doi: 10.1097/SHK.0000000000002605. Online ahead of print.

PMID: 40267485

 

 

AI-driven framework to map the brain metabolome in three dimensions.

Ma X, Shedlock CJ, Medina T, Ribas RA, Clarke HA, Hawkinson TR, Dande PK, Golamari HKR, Wu L, Ziani BE, Burke SN, Merritt ME, Vander Kooi CW, Gentry MS, Yadav NN, Chen L, Sun RC.

Nat Metab. 2025 Apr;7(4):842-853. doi: 10.1038/s42255-025-01242-9. Epub 2025 Mar 18.

PMID: 40102678

 

 

SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases.

Ku D, Yang Y, Park Y, Jang D, Lee N, Lee YK, Lee K, Lee J, Han YB, Jang S, Choi SR, Ha YJ, Choi YS, Jeong WJ, Lee YJ, Lee KJ, Cha S, Kim Y.

Cell Rep. 2025 Apr 19;44(5):115588. doi: 10.1016/j.celrep.2025.115588. Online ahead of print.

PMID: 40253699

 

 

Bacillus Calmette-Guérin Vaccination Promotes Efficient and Comprehensive Immune Modulation in Guinea Pig Models.

Ouh IO, Kim MJ, Kim K, Lim H, Yang YJ, Heo JW, Choi HN, Kim HH, Lee HJ, Koh PO, Moon SY, Choi EB, Lee YK, Park KI.

Vaccines (Basel). 2025 Mar 12;13(3):305. doi: 10.3390/vaccines13030305.

PMID: 40266210

 

 

antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation.

Blin K, Shaw S, Vader L, Szenei J, Reitz ZL, Augustijn HE, Cediel-Becerra JDD, de Crécy-Lagard V, Koetsier RA, Williams SE, Cruz-Morales P, Wongwas S, Segurado Luchsinger AE, Biermann F, Korenskaia A, Zdouc MM, Meijer D, Terlouw BR, van der Hooft JJJ, Ziemert N, Helfrich EJN, Masschelein J, Corre C, Chevrette MG, van Wezel GP, Medema MH, Weber T.

Nucleic Acids Res. 2025 Apr 25:gkaf334. doi: 10.1093/nar/gkaf334. Online ahead of print.

PMID: 40276974