UFGI Publication Round-Up: Week of 12/29/2025

Mills MN, Pacheo G, Tong AY, Tong EL, Hannani MA, Heganovic L, Fleary K, Shaffer SN, Vairavan MS, Ferré-D’Amaré AR, Passalacqua LFM, Abdelsayed MM.

J Biol Chem. 2025 Dec 30:111119. doi: 10.1016/j.jbc.2025.111119. Online ahead of print.

PMID: 41478572

Machine learning models predict long COVID outcomes based on baseline clinical and immunologic factors.

Doni Jayavelu N, Samaha H, Wimalasena ST, Hoch A, Gygi JP, Gabernet G, Ozonoff A, Liu S, Milliren CE, Levy O, Baden LR, Melamed E, Ehrlich LIR, McComsey GA, Sekaly RP, Cairns CB, Haddad EK, Schaenman J, Shaw AC, Hafler DA, Montgomery RR, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Agudelo Higuit NI, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Gen LN, Fernandez Sesma A, Simon V, Krammer F, Kraft M, Bime C, Calfee CS, Erle DJ, Langelier CR; IMPACC Network; Guan L, Maecker HT, Peters B, Kleinstein SH, Reed EF, Augustine AD, Diray-Arce J, Becker PM, Rouphael N, Altman MC.

Commun Med (Lond). 2026 Jan 3;6(1):1. doi: 10.1038/s43856-025-01230-w.

PMID: 41484172

Modified Fall Risk Appraisal Matrix and Mental Health in Community-Dwelling Older Adults.

Kim D, Thiamwong L, Li Y, Suarez JRM, Xie R, Wang Y, Loerzel V.

Clin Gerontol. 2025 Dec 29:1-9. doi: 10.1080/07317115.2025.2606696. Online ahead of print.

PMID: 41457967

Identification of Novel Susceptibility Genes for Early-Onset Colorectal Cancer Through Germline Rare Variant Burden Testing.

Song R, Mikaeel RR, He Z, Horsnell M, Uylaki W, Meng W, Poplawski NK, Wollnik B, Li Y, Feng J, Scott HS, Shen Y, Wang C, Yin R, Ding Y, Llor X, Chung WK, Smith E, Price TJ, Young JP, Fan X.

Cancers (Basel). 2025 Dec 9;17(24):3931. doi: 10.3390/cancers17243931.

PMID: 41463182

A double-blind, placebo-controlled, multi-crossover trial of treatment with a chemokine antagonist for knee osteoarthritis pain.

Edwards RR, Tarpey T, Ashburn M, Baer C, Campbell A, Dworkin RH, Gaspard G, Flynn M, Hade E, Jain N, Judge H, Kamp C, Li Y, Meropol S, Petkova E, Philip A, Przkora R, Rathmell JP, Robinson-Papp J, Samuels J, Seghal N, Sienty J, Stacey B, Wallace M, Wasan AD, Wise B, Yu C, Fava M, Troxel AB.

Pain. 2025 Dec 31. doi: 10.1097/j.pain.0000000000003904. Online ahead of print.

PMID: 41468282

The relationship between training load and injury risk in taekwondo: a systematic review.

Hu Y, Fu Z, Torres M, Luo W, Tang B, Zhu D, Zhao P, Li Y, Fong DTP, Wang D.

BMC Sports Sci Med Rehabil. 2026 Jan 2. doi: 10.1186/s13102-025-01481-z. Online ahead of print.

PMID: 41484800

Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in Clopidogrel-Treated Participants.

Ortega-Paz L, Thomas CD, Laudani C, Giordano S, Franchi F, Tunehag KR, Rollini F, Durukan S, Rossi JS, Farahmandsadr M, Stouffer GA, Been L, Keeley EC, Duarte JD, Beitelshees AL, Lee CR, Cavallari LH, Angiolillo DJ.

Clin Pharmacol Ther. 2026 Jan;119(1):168-178. doi: 10.1002/cpt.70045. Epub 2025 Aug 28.

PMID: 40875095

Global Investigation of Clinical Implementation Strategies for DPYD Testing to Guide Fluoropyrimidine Therapy.

El Rouby N, Aquilante CL, Bargal SA, Cavallari LH, Duarte JD, Gunderson K, Mazhindu T, Nagy M, Nie X, Nguyen DG, Patel JN, Skaar TC, Smith DM, Tuteja S, van Schaik RHN, Hicks JK; PGRN Implementation Working Group.

Clin Transl Sci. 2026 Jan;19(1):e70466. doi: 10.1111/cts.70466.

PMID: 41456101

Connectomic mapping of pharyngeal and gut sensory circuits in adult Drosophila.

Giakoumas DS, Zhu JM, Jamal A, Yao Z.

bioRxiv [Preprint]. 2025 Dec 16:2025.12.14.694216. doi: 10.64898/2025.12.14.694216.

PMID: 41446120

refineDLC: An advanced post-processing pipeline for DeepLabCut outputs.

Klecel W, Rahael H, Brooks SA.

Biol Methods Protoc. 2025 Dec 4;10(1):bpaf084. doi: 10.1093/biomethods/bpaf084. eCollection 2025.

PMID: 41467036

Intratumoral bacteria are immunosuppressive and promote immunotherapy resistance in head and neck squamous cell carcinoma.

Silver NL, Dai J, Kerr TD, Altemus J, Garg R, Simmons H, Alban T, Noel-Romas L, Makarov V, Shih DJH, Kumar SV, Santos A, Akbani R, Burgener A, Dwidar M, Gross N, Sikora AG, Sayour EJ, Stacy A, Jobin C, Chan TA, Ferrarotto R, McGrail DJ.

Nat Cancer. 2026 Jan 2. doi: 10.1038/s43018-025-01067-1. Online ahead of print.

PMID: 41482523

Multi-site, in vivo MRI dataset of brain diffusivity measures before and after harmonization, and atrophy measures following controlled cortical impact in male and female adult rats.

Kislik G, Fox R, Korotcov A, Zhou J, Febo M, Moghadas B, Bibic A, Zou Y, Wan J, Koehler RC, Adebayo T, Burns MP, McCabe JT, Wang KKW, Huie JR, Ferguson AR, Paydar A, Wanner IB, Harris NG; TOP-NT Investigators.

Front Neurol. 2025 Dec 15;16:1719618. doi: 10.3389/fneur.2025.1719618. eCollection 2025.

PMID: 41473220

Quest for Orthologs in the era of Data Deluge and AI: Challenges and Innovations in Orthology Prediction and Data Integration.

Majidian S, Hadziahmetovic A, Langschied F, Pascarelli S, Prieto-Baños S, Rojas-Vargas J; Quest for Orthologs Consortium; Braun EL, Dessimoz C, Diallo AB, Durand D, Fang G, Gabaldón T, Glover N, Liberles DA, McWhite C, Sonnhammer ELL, Thomas PD, Ouangraoua A, Julca I.

J Mol Evol. 2025 Dec;93(6):702-719. doi: 10.1007/s00239-025-10272-6. Epub 2025 Oct 14.

PMID: 41085653

The ubiquitin conjugating enzyme E2 F (UBE2F)-RING-box protein 2 (RBX2)-mediated neddylation of Cullin5 facilitates pseudorabies virus replication.

Zheng Z, Zhao F, Zhao S, Bai Y, Shi L, Zhu B, Huang X, Zheng Y, Zhao Q, Wen Y, Wu R, Du S, Cao S, Yan Q, Xu Z, Tibbetts SA, Wang Y.

Int J Biol Macromol. 2025 Dec 30:150018. doi: 10.1016/j.ijbiomac.2025.150018. Online ahead of print.

PMID: 41478481

IFN-γ-driven skewing towards Th1 over Th17 differentiation underlies CRS and neutropenia in CAR-T therapy.

Goala P, Zhang Y, Beatty N, Pavy A, McSain S, Sailer C, Tariq MJ, Hamid S, Cortes Gomez E, Wang J, Massillon D, Ilecki M, Boucher JC, Savid-Frontera C, Lee SB, Kotani H, Stone ML, Jain MD, Davila ML.

J Clin Invest. 2025 Oct 30;136(1):e194631. doi: 10.1172/JCI194631. eCollection 2026 Jan 2.

PMID: 41165751

IFN-γ-driven skewing towards Th1 over Th17 differentiation underlies CRS and neutropenia in CAR-T therapy.

Goala P, Zhang Y, Beatty N, Pavy A, McSain S, Sailer C, Tariq MJ, Hamid S, Cortes Gomez E, Wang J, Massillon D, Ilecki M, Boucher JC, Savid-Frontera C, Lee SB, Kotani H, Stone ML, Jain MD, Davila ML.

J Clin Invest. 2025 Oct 30;136(1):e194631. doi: 10.1172/JCI194631. eCollection 2026 Jan 2.

PMID: 41165751

Costs per responder for patients with relapsed or refractory multiple myeloma treated with Talquetamab compared with usual care.

Lee HC, Yang C, Liu YH, Mu F, Wang J, Goble J, Patel N, Zhang X, Grajales-Cruz AF, Jiao T.

J Med Econ. 2026 Dec;29(1):93-105. doi: 10.1080/13696998.2025.2604457. Epub 2026 Jan 3.

PMID: 41483183

Improving Assessment of Vaccine Effectiveness by Coupling Test-Negative Design Studies with Survival Models.

Song S, Hitchings M, Yang Y, Longini IM Jr.

medRxiv [Preprint]. 2025 Dec 6:2025.11.30.25341323. doi: 10.64898/2025.11.30.25341323.

PMID: 41409669

Correction: MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson’s HLA locus exhibits epigenetic regulation.

Kline EM, Jernigan JE, Scharer CD, Maurer J, Hicks SL, Herrick MK, Wallings RL, Kelly SD, Chang J, Menees KB, Manfredsson FP, McFarland NR, Boss JM, Tansey MG, Joers V.

Sci Rep. 2025 Dec 29;15(1):44842. doi: 10.1038/s41598-025-31393-4.

PMID: 41466060

Drug resistant cancer cells show increased nuclear mechanotransduction and mechanically targetable YAP-regulated vulnerability.

Huang M, Chen Y, Liang C, Narayan OP, Stallings C, Yu M, Traugot C, Li L, Li K, Vo Q, Wang H, Chou YT, Cech L, Parra D, Garzon L, Parsons D, Diaz E, Zhang C, Mackey C, Sussman H, Zmirska I, Chung M, Zhou C, Glynatsis G, Siemann DW, Licht JD, Li C, Kaye FJ, Xie M, Tan Y, Wu L, Bivona TG, Guan J, Tang X.

Biomaterials. 2025 Dec 15;329:123920. doi: 10.1016/j.biomaterials.2025.123920. Online ahead of print.

PMID: 41443038

Basic Science and Pathogenesis.

Torrellas J Jr, Chairmandurai A, Mamais A, LaVoie MJ, Chakrabarty P.

Alzheimers Dement. 2025 Dec;21 Suppl 1:e107448. doi: 10.1002/alz70855_107448.

PMID: 41454607

Cardiac troponin T elevation predicts mortality in hospitalized COVID-19 patients.

Bruno KA, Wright RS, Culberson J, Wieczorek MA, Hodge DO, Johnson PW, Jimenez YA, Whelan ER, Malavet JM, Larson KF, Senefeld JW, Wiggins CC, Klassen SA, Ricci J, Sher T, Carter RE, Joyner MJ, Fairweather D, Jaffe AS.

Am Heart J Plus. 2025 Dec 2;61:100690. doi: 10.1016/j.ahjo.2025.100690. eCollection 2026 Jan.

PMID: 41446701

Cosmetic Training Models in Academic Dermatology: Balancing Ethics, Equity and Patient Rights.

Kim J, Zieneldien T, Ma S, Tan IJ, Grant-Kels JM.

J Am Acad Dermatol. 2025 Dec 19:S0190-9622(25)03439-5. doi: 10.1016/j.jaad.2025.12.057. Online ahead of print.

PMID: 41422911

The effect of alternate wetting and drying (AWD) on spikelet fertility, grain traits and the biosynthesis of 2-acetyl-1-pyrroline (2-AP) in rice grown under high temperature.

Okpala NE, Du B, Bimpong D, Amenyogbe MK, Aloryi KD, Liu Y, Yan P, Chen L, Liu W, Wang G, Tian X, An T.

BMC Plant Biol. 2025 Dec 24;25(1):1725. doi: 10.1186/s12870-025-07694-1.

PMID: 41444869