UFGI Publication Round-Up: Week of 9/1/2025

UFGI Publication Round-Up: Week of 9/1/2025

Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease.

Fuller DD, Rana S, Thakre PP, Benevides ES, Pope MK, Todd AG, Jensen VN, Vaught L, Cloutier DA, Ribas RA, Larson RC, Gentry MS, Sun RC, Chandran V, Corti M, Falk DJ, Byrne BJ.

Mol Ther. 2025 Sep 3;33(9):4276-4289. doi: 10.1016/j.ymthe.2025.06.022. Epub 2025 Jun 14.

PMID: 40518673

 

 

Adaptive deep brain stimulation timed to gait phase improves walking in Parkinson’s disease.

Louie KH, Balakid JP, Bath JE, Song S, Fekri Azgomi H, Marks JH, Choi JT, Starr PA, Wang DD.

medRxiv [Preprint]. 2025 Aug 21:2025.08.19.25333759. doi: 10.1101/2025.08.19.25333759.

PMID: 40894140

 

 

How Do Patient Outcomes in Mechanical Thrombectomy for Large-Core Stroke Vary Based on Neuroimaging Modalities Used for Patient Selection? A Multicenter Multinational Study.

Alwakaa O, Abo Kasem R, Ramirez-Velandia F, Wadhwa A, Han K, Levitt MR, Alaraj A, Jabbour P, Kim JT, Howard B, Alawieh A, Wolfe SQ, Starke RM, Psychogios MN, Shaban A, Goyal N, Dye J, Ezzeldin M, Yoshimura S, Sconzo D, Filo J, Pettersson S, Fiorella D, Tanweer O, Romano DG, Navia P, Cuellar H, Fragata I, Polifka A, Mascitelli J, Osbun J, Siddiqui F, Moss M, Limaye K, Mokin M, Matouk C, Park MS, Brinjikji W, Daglioglu E, Williamson R Jr, Altschul DJ, Maier I, Crosa R, Gory B, Grandhi R, Paul A, Kan P, Casagrande W, Chowdhry S, Stiefel MF, Rai A, Spiotta AM, Taussky P, Ogilvy CS, Granstein JH.

Transl Stroke Res. 2025 Sep 3. doi: 10.1007/s12975-025-01378-6. Online ahead of print.

PMID: 40900221

 

 

Moderating effects of plasma glial fibrillary acidic protein along the Alzheimer’s disease continuum.

Lee SY, Diaz VE, Emanuel OM, Matusz EF, Webb J, Chan B, Lago AL, Wang WE, DeSimone J, Rojas JC, VandeVrede L, La Joie R, Levy SA, Arias F, Wiens BA, Velez-Uribe I, Barker WW, Paolillo EW, Sanderson-Cimino M, Rosselli M, Rayaprolu S, Rundek T, Curiel Cid RE, Vaillancourt DE, Armstrong MJ, Marsiske M, DeKosky ST, Loewenstein DA, Duara R, Smith GE, Staffaroni A, Rabinovici GD, Casaletto KB, Kramer JH, Saloner R, Asken BM.

Alzheimers Dement. 2025 Sep;21(9):e70626. doi: 10.1002/alz.70626.

PMID: 40911721

 

 

A single-cell, long-read, isoform-resolved case-control study of FTD reveals cell-type-specific and broad splicing dysregulation in human brain.

Belchikov N, Hu W, Fan L, Joglekar A, He Y, Foord C, Jarroux J, Hsu J, Pollard S, Amin S, Prjibelski AD, Gong S, Zhang S, Giannelli R, Seelaar H, Tomescu AI, Ross ME, Li AN, Grinberg LT, Spina S, Miller BL, Cooper-Knock J, Snyder MP, Seeley WW, Rao-Ruiz P, Spijker S, Smit AB, Clelland CD, Gan L, Tilgner HU.

Cell Rep. 2025 Sep 5;44(9):116198. doi: 10.1016/j.celrep.2025.116198. Online ahead of print.

PMID: 40913764

 

 

Targeted degradation of NPR3 confers broad-spectrum resistance in wheat.

Zhou M, Mou Z.

Mol Plant. 2025 Sep 4:S1674-2052(25)00310-7. doi: 10.1016/j.molp.2025.09.004. Online ahead of print.

PMID: 40913311

 

 

Targeting deubiquitinating enzymes and ubiquitin pathway modulators to enhance host defense against bacterial infections.

Santelices J, Schultz A, Walker A, Adams N, Tirado D, Barker H, Eshraghi A, Czyż DM, Ferraro MJ.

mBio. 2025 Sep 3:e0031225. doi: 10.1128/mbio.00312-25. Online ahead of print.

PMID: 40899844

 

 

Environmentally relevant levels of sulfamethoxazole (SMX) alter the skin and gastrointestinal microbiome of adult male and female zebrafish (Danio rerio).

Iftikhar N, Konig I, Brammer-Robbins E, Kozuch M, Bisesi JH Jr, Hashmi I, Martyniuk CJ.

Aquat Toxicol. 2025 Aug 19;288:107546. doi: 10.1016/j.aquatox.2025.107546. Online ahead of print.

PMID: 40886646

 

 

Retrograde lumbar vein flow and epidural venous congestion in chronic headache patients with or without nutcracker phenomenon: An expanded database of 98 patients.

Ogunlade SB, Arora M, Rozen T, Lewis AR, Toskich BB, Fairweather D, Bruno KA, Devcic Z.

Eur J Radiol. 2025 Oct;191:112319. doi: 10.1016/j.ejrad.2025.112319. Epub 2025 Jul 15.

PMID: 40682980

 

 

Improved injury detection through harmonizing multi-site neuroimaging data after experimental TBI: a Translational Outcomes Project in Neurotrauma consortium study.

Kislik G, Fox R, Korotcov AV, Zhou J, Febo M, Moghadas B, Bibic A, Zou Y, Wan J, Koehler RC, Adebayo T, Burns MP, McCabe JT, Wang KK, Huie JR, Ferguson AR, Paydar A, Wanner IB, Harris NG; TOP-NT Investigators.

Front Neurol. 2025 Aug 20;16:1612598. doi: 10.3389/fneur.2025.1612598. eCollection 2025.

PMID: 40909007

 

 

Changing Epidemiology, Outcomes, and Testing for HPV-Associated Sinonasal Squamous Cell Carcinoma: Should Routine HPV Testing Be Encouraged?

Adelman A, Lee Y, Im E, Lobo BC, Justice JM, Chapurin N.

Int Forum Allergy Rhinol. 2025 Sep;15(9):985-988. doi: 10.1002/alr.23611. Epub 2025 May 19.

PMID: 40387027

 

 

Dual S100A1 and ARC gene therapy as a treatment for DMD cardiomyopathy.

Hammers DW, Hart CC, Lee YI, Sleeper MM, Sweeney HL.

bioRxiv [Preprint]. 2025 Aug 23:2025.08.23.671924. doi: 10.1101/2025.08.23.671924.

PMID: 40894611

 

 

33 Unresolved Questions in Nanoscience and Nanotechnology.

Mirkin CA, Petrosko SH, Artzi N, Aydin K, Biaggne A, Brinker CJ, Bujold KE, Cao YC, Chan RR, Chen C, Chen PC, Chen X, Chevalier OJGL, Choi CHJ, Crooks RM, Dravid VP, Du JS, Ebrahimi SB, Fan H, Farha OK, Figg CA, Fink TD, Forsyth CM, Fuchs H, Geiger FM, Gianneschi NC, Gibson KJ, Ginger DS, Guo S, Hanes JS, Hao L, Huang J, Hunter BM, Huo F, Hwang J, Jin R, Kelley SO, Kempa TJ, Kim Y, Kudruk S, Kumari S, Landy KM, Lee KB, Leon NJ, Li J, Li Y, Li Z, Liu B, Liu G, Liu X, Liz-Marzán LM, Lorch JH, Luo T, Macfarlane RJ, Millstone JE, Mrksich M, Murphy CJ, Naik RR, Nel AE, Oetheimer C, Hedlund Orbeck JK, Park SJ, Partridge BE, Peppas NA, Personick ML, Raj A, Ramani N, Ross MB, Ross SB, Sargent EH, Sengupta T, Schatz GC, Seferos DS, Seideman T, Seo SE, Shen B, Shim W, Shin D, Simon U, Sinegra AJ, Smith PT, Spokoyny AM, Stang PJ, Stegh AH, Stoddart JF, Swearer DF, Tan W, Teplensky MH, Thaxton CS, Walt DR, Wang MX, Wang Z, Wei WD, Weiss PS, Winegar PH, Xia Y, Xie Y, Xu X, Yang P, Yang Y, Ye Z, Yoon KR, Zhang C, Zhang H, Zhang K, Zhang L, Zhang X, Zhang Y, Zheng Z, Zhou W, Zhu S, Zhu W.

ACS Nano. 2025 Sep 4. doi: 10.1021/acsnano.5c12854. Online ahead of print.

PMID: 40905551

 

 

Opportunities and considerations for using artificial intelligence in bioinformatics education.

Piccolo SR, Nathan A, Brazas MD, Kandpal M, Miró-Herrans AT, Kleinschmit AJ, McClatchy S, Mutheiwana P, Nikolic D, Gallo LI, Julius RS, Lloret-Llinares M, Mulder N, Presgraves D, Shewaramani S, Xool-Tamayo J, Chain FJJ, Sanchez Guerrero SA.

Bioinform Adv. 2025 Sep 1;5(1):vbaf169. doi: 10.1093/bioadv/vbaf169. eCollection 2025.

PMID: 40900913

 

Refugial isolation and ecological niche differentiation promote genetic divergence of Oresitrophe and Mukdenia in Northeast Asia.

Xia M, Lee J, Yu L, Mu X, Jiang WM, Soltis DE, Liu L, Li P.

Am J Bot. 2025 Sep 4:e70088. doi: 10.1002/ajb2.70088. Online ahead of print.

PMID: 40904271

 

 

REV-ERBα regulates brain NAD+ levels and tauopathy via an NFIL3-CD38 axis.

Lee J, Kang R, Park S, Saliu IO, Son M, Voorhees JR, Dimitry JM, Quillin EI, Woodie LN, Lananna BV, Gan L, Goo YA, Zhao G, Lazar MA, Burris TP, Musiek ES.

Nat Aging. 2025 Sep 1. doi: 10.1038/s43587-025-00950-x. Online ahead of print.

PMID: 40890338

 

 

Subcortical brain volume variations in autistic individuals across the lifespan.

Christensen D, Shin YS, Wang J, Cuomo CR, Dentry T, Gemmell HM, Pulver SL, Orlando AM, McKinney WS, Stevens CJ, Unruh KE, Karmakar B, Coombes SA, Mosconi MW, Wang Z.

Mol Autism. 2025 Sep 1;16(1):46. doi: 10.1186/s13229-025-00673-1.

PMID: 40887620

 

 

Explainable machine learning reveals climate warming increases risk of algal blooms in lakes and reservoirs.

Ma Y, Wang J, Huo S, Wang D, Wang Y, Li J, Chen J, Feng L.

Water Res. 2025 Aug 25;287(Pt B):124460. doi: 10.1016/j.watres.2025.124460. Online ahead of print.

PMID: 40902384

 

 

Genome-wide association study and fine-mapping using imputed sequences to prioritize candidate genes for 30 complex traits in 50,309 Holstein bulls.

Wang J, Gao Y, Toghiani S, Cole JB, Maltecca C, Ma L, Jiang J.

J Dairy Sci. 2025 Sep 3:S0022-0302(25)00724-6. doi: 10.3168/jds.2025-27058. Online ahead of print.

PMID: 40912550

 

 

Associations between prepartum urine pH and periparturient blood calcium concentrations in multiparous Holstein cows.

Goff JP, Melendez P, Bartolome JA, Overton TR, Leno BM, Graef G, Drackley JK, Glosson KM, Zhang X, LeBlanc SJ, Couto-Serrenho R, Santos JEP, Lopera C, Zimpel R, Rodney RM, Lean IJ.

Front Vet Sci. 2025 Aug 20;12:1649751. doi: 10.3389/fvets.2025.1649751. eCollection 2025.

PMID: 40909939

 

 

Manipulation of the Symbiodiniaceae microbiome confers multigenerational impacts on symbioses and reproductive ecology of its Exaiptasia diaphana host.

McCauley M, Montesanto F, Bedgood SA, Miner C, Plichon K, Weis VM, Loesgen S.

ISME J. 2025 Sep 2:wraf189. doi: 10.1093/ismejo/wraf189. Online ahead of print.

PMID: 40891513

 

 

Multichassis Expression of Cyanobacterial and Other Bacterial Biosynthetic Gene Clusters.

Dhakal D, Eckhardt CW, Jiang Y, Luesch H, Ding Y.

ACS Synth Biol. 2025 Sep 2. doi: 10.1021/acssynbio.5c00390. Online ahead of print.

PMID: 40891916

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