UFGI Publication Round-Up: Week of 6/30/2025

UFGI Publication Round-Up: Week of 6/30/2025

Targeted genome mining with GATOR-GC maps the evolutionary landscape of biosynthetic diversity.

Cediel-Becerra JDD, Cumsille A, Guerra S, Ding Y, de Crécy-Lagard V, Chevrette MG.

Nucleic Acids Res. 2025 Jul 8;53(13):gkaf606. doi: 10.1093/nar/gkaf606.

PMID: 40626555

 

 

Predictive modeling of ARDS mortality integrating biomarker/cytokine, clinical and metabolomic data.

Rafikov R, Thompson DM, Rafikova O, Camp SM, Ribas RA, Sun RC, Gentry MS, Casanova NG, Garcia JGN.

Transl Res. 2025 Jul;281:31-42. doi: 10.1016/j.trsl.2025.05.005. Epub 2025 May 24.

PMID: 40419238

 

 

Development of an electronic health record-based Human Immunodeficiency Virus (HIV) risk prediction model for women, incorporating social determinants of health.

Liu Y, Chen A, Cho H, Siddiqi KA, Cook RL, Prosperi M.

BMC Public Health. 2025 Jul 2;25(1):2257. doi: 10.1186/s12889-025-23460-2.

PMID: 40604593

 

 

CYP2C19 Phenotype, P2Y12 Inhibitor Selection, and Clinical Outcomes in Patients on Maintenance Clopidogrel Therapy.

Patel RC, Thomas CD, Rossi JS, Franchi F, Keeley EC, Beitelshees AL, Duarte JD, Ortega-Paz L, Kulick N, Winget M, Nguyen AB, Yang WE, Venkatesh S, Angiolillo DJ, Cavallari LH, Lee CR, Stouffer GA.

J Am Heart Assoc. 2025 Jul 3:e041634. doi: 10.1161/JAHA.125.041634. Online ahead of print.

PMID: 40611487

 

 

Living with males leads to female physical injury in the leaf-footed cactus bug.

Li Y, Miller CW.

Behav Ecol. 2025 Jun 11;36(4):araf068. doi: 10.1093/beheco/araf068. eCollection 2025 Jul-Aug.

PMID: 40589605

 

 

GNAT family Pat2 lysine acetylation of glycerol kinase and its key role in glycerol metabolism in hypersaline-adapted archaea.

Judd HN, Sanchez KM, Dublino LS, Zhang GJ, Gal D, Couto-Rodríguez RL, Maupin-Furlow JA.

bioRxiv [Preprint]. 2025 May 28:2025.05.27.656527. doi: 10.1101/2025.05.27.656527.

PMID: 40501657

 

 

Revisiting synthetic lethality of Gcn5-related N-acetyltransferase (GNAT) family mutations in Haloferax volcanii.

Weber KR, Novillo B, Maupin-Furlow JA.

Microbiol Spectr. 2025 Jul 2:e0122925. doi: 10.1128/spectrum.01229-25. Online ahead of print.

PMID: 40600719

 

 


Exploring age-related iron dysregulation: Effects on longevity, body size, and behavior in C. elegans.

Zeidan RS, Ebea-Ugwuanyi P, Sykes S, Evripidou N, Pan E, Markovich Z, Sheng Y, Han SM, Leeuwenburgh C, Xiao R.

Exp Gerontol. 2025 Jul 3:112826. doi: 10.1016/j.exger.2025.112826. Online ahead of print.

PMID: 40617521

 

 


Blocking immune checkpoint LAIR1 with antibody blockade or 3-in-1 CAR T cells enhances antitumor response.

Tao H, Chen D, Yang C, Nguyen DT, Abboud G, Liu R, Liu T, Chakraborty A, Hou AY, Petit NA, Abbas M, Davis RW, Zhang J, Von Roemeling C, Gbadamosi MO, Jin L, Gu T, Lin T, Wang P, Pepe A, Pedro DI, Mendez-Gomez HR, Xie C, Karachi A, Weidert F, Jin D, Wang C, Long-James K, Molchan EK, Castillo P, Ligon JA, Ghiaseddin AP, Sayour EJ, Rahman M, Deleyrolle LP, Kim BY, Mitchell DA, Sawyer WG, Huang J.

J Clin Invest. 2025 Jul 1:e184043. doi: 10.1172/JCI184043. Online ahead of print.

PMID: 40591413

 

 

Nanomaterial isolated extracellular vesicles enable high precision identification of tumor biomarkers for pancreatic cancer liquid biopsy.

Greenberg ZF, Ali S, Brock A, Jiang J, Schmittgen TD, Han S, Hughes SJ, Graim KS, He M.

J Nanobiotechnology. 2025 Jul 1;23(1):467. doi: 10.1186/s12951-025-03527-3.

PMID: 40598203

 

 

DR5 Disulfide Bonding Functions as a Sensor and Effector of Protein Folding Stress.

Law ME, Dulloo ZM, Eggleston SR, Takacs GP, Alexandrow GM, Lee YI, Wang M, Hardy B, Su H, Forsyth B, Das P, Datta PK, Chiang CW, Sharma A, Kanumuri SRR, Guryanova OA, Harrison JK, Tirosh B, Castellano RK, Law BK.

Mol Cancer Res. 2025 Jul 2;23(7):622-639. doi: 10.1158/1541-7786.MCR-24-0756.

PMID: 40105733

 

 


A case-cohort longitudinal study for the analysis of microbial associations and viruses on the risk of celiac disease (MAVRiC).

Lynch KF, Triplett EW, Hyöty H, Ahrens AP, Laiho JE, Petrosino JF, Lloyd RE, Agardh D.

medRxiv [Preprint]. 2025 May 27:2025.05.26.25328184. doi: 10.1101/2025.05.26.25328184.

PMID: 40492061

 

 

Searching for druggable targets.

Heganovic L, Passalacqua LFM.

Elife. 2025 Jul 2;14:e107757. doi: 10.7554/eLife.107757.

PMID: 40600391

 

 

Stromal Vascular Fraction-Derived Vasculogenesis Is Associated with the Formation of Lymphatic Endothelial Cell Structures.

Hu NW, Shang H, Kogan S, Llull R, Traktuev DO, Katz AJ, Murfee WL.

Stem Cells Dev. 2025 Jul;34(13-14):280-290. doi: 10.1089/scd.2024.0210. Epub 2025 Jun 19.

PMID: 40533090

 

 

Aerobic exercise-induced changes in fluid biomarkers in Parkinson’s disease.

Luthra NS, Mehta N, Munoz MJ, Fantuzzi G, Lamotte G, Haus JM, McFarland NR, Tansey MG, Gonzalez-Latapi P, Caraveo G, Kang UJ, Corcos DM.

NPJ Parkinsons Dis. 2025 Jul 1;11(1):190. doi: 10.1038/s41531-025-01042-8.

PMID: 40595707

 

 

Epigenetic age acceleration and psychosocial stressors in early childhood.

Mulligan CJ.

Epigenomics. 2025 Jul;17(10):701-710. doi: 10.1080/17501911.2025.2508684. Epub 2025 Jun 2.

PMID: 40454979

 

 

Complement Activation in a Phase Ib Study of Fordadistrogene Movaparvovec for Duchenne Muscular Dystrophy.

Byrne BJ, Butterfield RJ, Shieh PB, Smith EC, Licht C, Binks M, Casinghino S, Delnomdedieu M, Ravindra KC, McDonnell T, Ryan K, Schulz M, Shen Q, Shi H, Sirivelu MP, Vaidya VS, Whiteley L, Levy DI.

Mol Ther. 2025 Jun 28:S1525-0016(25)00483-6. doi: 10.1016/j.ymthe.2025.06.032. Online ahead of print.

PMID: 40583275

 


The influence of prestroke disability on outcome in patients with a low Alberta Stroke Program Early CT Score who underwent endovascular thrombectomy.

Matsukawa H, Uchida K, Elawady SS, Cunningham C, Sowlat MM, Maier I, Jabbour P, Kim JT, Wolfe SQ, Rai A, Starke RM, Psychogios MN, Samaniego EA, Arthur AS, Yoshimura S, Cuellar-Saenz H, Grossberg JA, Alawieh A, Romano DG, Tanweer O, Mascitelli J, Fragata I, Polifka A, Osbun J, Crosa R, Matouk C, Park MS, Levitt MR, Brinjikji W, Moss M, Williamson R, Navia P, Kan P, De Leacy R, Chowdhry S, Ezzeldin M, Spiotta AM.

J Neurosurg. 2025 Feb 7;143(1):266-273. doi: 10.3171/2024.10.JNS24888. Print 2025 Jul 1.

PMID: 39919282

 

 

Total synthesis and algaecidal activity of questiomycins against harmful bloom forming dinoflagellates.

Yang S, Aryal N, Azmi SNQB, Wang Y, Burchill L, Meke LE, Durham BP, Williams SJ.

Chem Commun (Camb). 2025 Jun 30. doi: 10.1039/d5cc02853a. Online ahead of print.

PMID: 40583625

 

 

HAPLOTYPE DIVERSITY IN ENDOSYMBIOTIC BACTERIA FOLLOWING A HOST SWITCH BY PARASITIC LICE.

Boyd BM, House N, Toloza AC, Reed DL.

J Parasitol. 2025 Jul 1;111(4):412-418. doi: 10.1645/24-148.

PMID: 40588254

 

 

Acceptance of crop biotechnology requires a change in communication strategy.

Folta KM.

Plant Physiol. 2025 Jul 3;198(3):kiaf167. doi: 10.1093/plphys/kiaf167.

PMID: 40314159

 

 

Anticoagulant therapy and altered tissue factor expression protect against experimental placental and cerebral malaria.

Andrew AK, Bracken TC, Nazario-Maldonado NM, Russ BN, Gonzalvo KT, Brainard BM, Mackman N, Moore JM.

PLoS Pathog. 2025 Jul 3;21(7):e1013259. doi: 10.1371/journal.ppat.1013259. Online ahead of print.

PMID: 40608830

 

 

A scoping review of human papillomavirus related data system in China.

Li Y, Wang R, Zhang J, Chen YT, Zhan S, Guo Y, Wang W.

BMC Infect Dis. 2025 Jul 1;25(1):873. doi: 10.1186/s12879-025-11106-y.

PMID: 40597707

 

 

Neighborhood deprivation and mortality among people with Alzheimer’s disease and related dementia.

Paley JL, Scheiffele GD, Li Y, Shaaban CE, Wu Y, Anton S, DeKosky S, Bian J, Guo J.

J Alzheimers Dis. 2025 Jul 2:13872877251352120. doi: 10.1177/13872877251352120. Online ahead of print.

PMID: 40605436

 

 

Abiotic conditions can modify the penetrance of transgene-based lethality systems for insect population control.

Pérez Gálvez FR, Handler AM, Hahn D, Bredlau JP, Teets NM.

Proc Biol Sci. 2025 Jul;292(2050):20250307. doi: 10.1098/rspb.2025.0307. Epub 2025 Jul 2.

PMID: 40592455

 

 

Translocation of gut bacteria promotes tumor-associated mortality by inducing immune-activated renal damage.

Cong F, Bao H, Wang X, Tang Y, Bao Y, Poulton JS, Liu X, Wong AC, Ji X, Deng WM.

EMBO J. 2025 Jul;44(13):3586-3613. doi: 10.1038/s44318-025-00458-5. Epub 2025 May 22.

PMID: 40404992

 

 

Animal Models of Exercise and Cardiometabolic Disease.

Dong G, Ryan TE, Esser KA.

Circ Res. 2025 Jul 7;137(2):139-162. doi: 10.1161/CIRCRESAHA.124.325704. Epub 2025 Jul 3.

PMID: 40608858

 

 


Long-term exposure to multiple air pollutants and multi-level socioeconomic status: joint effects on age-related macular degeneration, subsequent ocular comorbidity, and death in middle-aged and older adults.

Yang Y, Chen L, Liu Q, Mu M, Huang J, Zhang G, Song Q.

BMC Med. 2025 Jul 1;23(1):354. doi: 10.1186/s12916-025-04224-6.

PMID: 40597158

 

 


Enhanced antitumor immunity of VNP20009-CCL2-CXCL9 via the cGAS/STING axis in osteosarcoma lung metastasis.

Liu R, Liu Q, Wang Y, Liu T, Zhang Z, Zhao C, Tao H, Ogando-Rivas E, Castillo P, Zhang W.

J Immunother Cancer. 2025 Jul 1;13(7):e012269. doi: 10.1136/jitc-2025-012269.

PMID: 40592739

 

 

Sirolimus Use During Pregnancy in Women with Lymphangioleiomyomatosis.

Krishna R, Johnson SR, Ataya A, Baqir M, Baldi BG, Girod CE, Diesler R, Henske EP, Xu KF, Gupta N.

Ann Am Thorac Soc. 2025 Jun 30. doi: 10.1513/AnnalsATS.202504-433RL. Online ahead of print.

PMID: 40587229

 

 


The Psychiatric Genomics Consortium: discoveries and directions.

Agrawal A, Bulik CM, Abebe DS, Andreassen OA, Atkinson EG, Choi KW, Corvin A, Davies HL, Davis LK, Docherty AR, Edenberg HJ, Franke B, Gelernter J, Giusti-Rodríguez P, Hettema JM, Hjerling-Leffler J, Huang H, Johnson EC, Lewis CM, Lu Y, Lynall ME, Martin J, McIntosh AM, Montalvo-Ortiz JL, Mullins N, Nievergelt CM, O’Connell KS, O’Donovan MC, Okewole A, Peterson RE, Posthuma D, Sebat J, Smoller JW, Sud R, Viswanath B, Walters JTR, Won H, Wray NR, Sullivan PF; Coordinating Committee of the Psychiatric Genomics Consortium.

Lancet Psychiatry. 2025 Jun 26:S2215-0366(25)00124-5. doi: 10.1016/S2215-0366(25)00124-5. Online ahead of print.

PMID: 40582370

 

 

MICBG406A polymorphism reduces risk of mechanical ventilation and death during viral acute lung injury.

Pickering H, Alipanah-Lechner N, Chen E, Duchen D, Maecker HT, Kim-Schulze S, Montgomery RR, Cotsapas C, Steen H, Krammer F, Langelier CR, Levy O, Baden LR, Melamed E, Ehrlich LI, McComsey GA, Sekaly RP, Cairns CB, Haddad EK, Shaw AC, Hafler DA, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Agudelo Higuita NI, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Fernandez-Sesma A, Simon V, Kraft M, Bime C, Erle DJ, Schaenman J, Ozonoff A, Peters B, Kleinstein SH, Augustine AD, Diray-Arce J, Becker PM, Rouphael N, Altman MC, Bosinger SE, Eckalbar WL, Network I, Calfee CS, Aguilar OA, Reed EF, Greenland JR, Calabrese DR.

JCI Insight. 2025 Jul 3:e191951. doi: 10.1172/jci.insight.191951. Online ahead of print.

PMID: 40608426

 

 

Three Xanthomonas Cell Wall Degrading Enzymes and Sorghum Brown midrib12 Contribute to Virulence and Resistance in the Bacterial Leaf Streak Pathosystem.

Wang Q, Veley KM, Johnson JMB, Sumner J, van Erven G, Kabel MA, Dhungana S, Berry J, Boyher A, Braun DM, Vermerris W, Bart RS.

Mol Plant Microbe Interact. 2025 May;38(3):400-410. doi: 10.1094/MPMI-05-24-0051-R. Epub 2025 Mar 13.

PMID: 39928577

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