UFGI Publication Round-Up: Week of 03/31/2025

Chang MC, Malut VR, Mahar R, Rushin A, McLeod MA, Pierre GL, Malut IR, Staklinski SJ, Glanz ME, Ragavan M, Sharma G, Madheswaran M, Badar A, Rao AD, Law BK, Kilberg MS, Collins JHP, Kodibagkar VD, Bankson JA, DeBerardinis RJ, Merritt ME.

Sci Adv. 2025 Mar 28;11(13):eadr0568. doi: 10.1126/sciadv.adr0568. Epub 2025 Mar 26.

PMID: 40138413

PERRC: Protease Engineering with Reactant Residence Time Control.

Nelson S, Gaza J, Ajayebi S, Masse R, Pho R, Scutero C, Martinusen S, Long L, Menezes A, Perez A, Denard C.

bioRxiv [Preprint]. 2025 Mar 4:2025.03.02.641063. doi: 10.1101/2025.03.02.641063.

PMID: 40093119

Generation of Population-Level Diversity in Anaplasma phagocytophilum msp2/p44 Gene Repertoires Through Recombination.

Barbet AF, Allred DR, Crosby FL.

Pathogens. 2025 Feb 27;14(3):233. doi: 10.3390/pathogens14030233.

PMID: 40137718

Inter-Dose Variability of Immunosuppressant Medication Among Adolescent Heart Transplants During Video Directly Observed Therapy.

Killian MO, Mayewski SE, Brumm SE, Wissner W, Davis RW 4th, Gupta D.

Pediatr Transplant. 2025 May;29(3):e14851. doi: 10.1111/petr.14851.

PMID: 40135390

The need for a type 1 diabetes scorecard.

de Beaufort C, Beran D, Ajmal S, Ramaiya K, Zafra-Tanaka JH, Atkinson M; Lancet Diabetes & Endocrinology Commission on type 1 diabetes.

Lancet Diabetes Endocrinol. 2025 Apr;13(4):277-278. doi: 10.1016/S2213-8587(25)00057-9.

PMID: 40148064

The Genetic Epidemiology of Parkinson’s Disease view.

Farrer MJ; GEoPD.

Lancet Neurol. 2025 Apr;24(4):285. doi: 10.1016/S1474-4422(25)00072-9.

PMID: 40120605

Psychiatric Genetics in Clinical Practice: Essential Knowledge for Mental Health Professionals.

Besterman AD, Alnor MA, Castaño M, DeLisi LE, Grice DE, Lohoff FW, Middeldorp CM, Müller DJ, Quattrone D, Nurnberger J Jr, Nurmi EL, Ross DA, Soda T, Schulze TG, Trost B, Vilella E, Yap CX, Zai G, Moreno-De-Luca D.

Am J Psychiatry. 2025 Mar 26:appiajp20240295. doi: 10.1176/appi.ajp.20240295. Online ahead of print.

PMID: 40134266

Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort.

Younes K, Johns E, Young CB, Kennedy G, Mukherjee S, Vossler HA, Winer J, Cody K, Henderson VW, Poston KL, Betthauser TJ, Bevis B, Brooks WM, Burns JM, Coombes SA, DeCarli C, DiFilippo FP, Duara R, Fan AP, Gibbons LE, Golde T, Johnson SC, Lepping RJ, Leverenz J, McDougall S, Rogalski E, Sanders E, Pasaye J, Sridhar J, Saykin AJ, Sridharan A, Swerdlow R, Trittschuh EH, Vaillancourt D, Vidoni E, Wang WE, Mez J, Hohman TJ, Tosun D, Biber S, Kukull WA, Crane PK, Mormino EC.

Alzheimers Dement. 2025 Mar;21(3):e70075. doi: 10.1002/alz.70075.

PMID: 40145384

Immune cell metabolic dysfunction in Parkinson’s disease.

Mark JR, Tansey MG.

Mol Neurodegener. 2025 Mar 24;20(1):36. doi: 10.1186/s13024-025-00827-y.

PMID: 40128809

Integrative species delimitation reveals an Idaho-endemic ground squirrel, Urocitellus idahoensis (Merriam 1913).

McLean BS, Rickart EA, Cook JA, Guralnick RP, Burgin CJ, Lohr K.

J Mammal. 2024 Dec 12;106(2):406-430. doi: 10.1093/jmammal/gyae135. eCollection 2025 Apr.

PMID: 40144356

López-Pérez K, Avellaneda-Tamayo JF, Chen L, López-López E, Juárez-Mercado KE, Medina-Franco JL, Miranda-Quintana RA.

Artif Intell Chem. 2024 Dec;2(2):100077. doi: 10.1016/j.aichem.2024.100077. Epub 2024 Aug 31.

PMID: 40124654

Expression of Fluorescence Reporters and Natural Products in Native Gut Escherichia coli.

Liu D, Ton PM, Zong D, Zarrinpar A, Ding Y.

ACS Synth Biol. 2025 Mar 26. doi: 10.1021/acssynbio.4c00835. Online ahead of print.

PMID: 40138712

A thiouracil desulfurase protects Clostridioides difficile RNA from 4-thiouracil incorporation, providing a competitive advantage in the gut.

Munneke MJ, Yuan Y, Preisner EC, Shelton CD, Carroll DT, Kirchoff NS, Dickson KP, Cantu JO, Douglass MV, Calcutt MW, Gibson-Corley KN, Nicholson MR, Byndloss MX, Britton RA, de Crécy-Lagard V, Skaar EP.

Cell Host Microbe. 2025 Mar 18:S1931-3128(25)00066-6. doi: 10.1016/j.chom.2025.03.001. Online ahead of print.

PMID: 40139192

Evaluating the feasibility, acceptability, and preliminary effectiveness of tele-comprehensive behavior therapy for tics (teleCBIT) for Tourette syndrome in youth and adults.

Capriotti MR, Wellen BC, Young BN, Himle MB, Conelea CA, Espil FM, Simpson H, Mathews CA.

J Telemed Telecare. 2025 Apr;31(3):328-337. doi: 10.1177/1357633X231189305. Epub 2023 Aug 7.

PMID: 37545359

Immune modulation to treat Alzheimer’s disease.

Duggan MR, Morgan DG, Price BR, Rajbanshi B, Martin-Peña A, Tansey MG, Walker KA.

Mol Neurodegener. 2025 Mar 31;20(1):39. doi: 10.1186/s13024-025-00828-x.

PMID: 40165251

Case report: Novel homozygous ACVRL1 missense variant in a family with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension: findings suggest a hypomorphic allele.

Mathavan A, Mathavan A, Krekora U, Rao A, Zumberg MS, Justice J, Bayrak-Toydemir P, McDonald J, Ataya A.

Front Genet. 2025 Mar 14;16:1554624. doi: 10.3389/fgene.2025.1554624. eCollection 2025.

PMID: 40160294

OLTA: Optimizing bait seLection for TArgeted sequencing.

Minbay MO, Sun R, Ramachandran V, Ay A, Kahveci T.

Bioinformatics. 2025 Apr 2:btaf146. doi: 10.1093/bioinformatics/btaf146. Online ahead of print.

PMID: 40175314

Feeding rumen-protected choline during the periconceptional period programs postnatal phenotype of suckled beef calves.

Sagheer M, Haimon MLJ, Montoya SH, Heredia D, Tarnonsky F, Venturini ME, Gonella-Diaza A, DiLorenzo N, McFadden JW, Dalmaso de Melo G, Pohler KG, Hansen PJ.

J Anim Sci Biotechnol. 2025 Apr 2;16(1):48. doi: 10.1186/s40104-025-01188-8.

PMID: 40170061

Transcriptomic and genetic analysis suggests a role for mitochondrial dysregulation in schizophrenia.

Bast L, Yao S, Martínez-López JA, Memic F, French H, Valiukonyte M, Karlsson R, Wen J, Song J, Zhang R, Abrantes A, Koopmans F, Österholm AM, Rosoklija G, Mann JJ, Stankov A, Trencevska I, Dwork A, Stockmeier CA, Love MI, Giusti-Rodriguez P, Smit AB, Sullivan PF, Hjerling-Leffler J.

medRxiv [Preprint]. 2025 Mar 15:2025.03.14.25323827. doi: 10.1101/2025.03.14.25323827.

PMID: 40162239

Psychiatric genetics in the diverse landscape of Latin American populations.

Bruxel EM, Rovaris DL, Belangero SI, Chavarría-Soley G, Cuellar-Barboza AB, Martínez-Magaña JJ, Nagamatsu ST, Nievergelt CM, Núñez-Ríos DL, Ota VK, Peterson RE, Sloofman LG, Adams AM, Albino E, Alvarado AT, Andrade-Brito D, Arguello-Pascualli PY, Bandeira CE, Bau CHD, Bulik CM, Buxbaum JD, Cappi C, Corral-Frias NS, Corrales A, Corsi-Zuelli F, Crowley JJ, Cupertino RB, da Silva BS, De Almeida SS, De la Hoz JF, Forero DA, Fries GR, Gelernter J, González-Giraldo Y, Grevet EH, Grice DE, Hernández-Garayua A, Hettema JM, Ibáñez A, Ionita-Laza I, Lattig MC, Lima YC, Lin YS, López-León S, Loureiro CM, Martínez-Cerdeño V, Martínez-Levy GA, Melin K, Moreno-De-Luca D, Muniz Carvalho C, Olivares AM, Oliveira VF, Ormond R, Palmer AA, Panzenhagen AC, Passos-Bueno MR, Peng Q, Pérez-Palma E, Prieto ML, Roussos P, Sanchez-Roige S, Santamaría-García H, Shansis FM, Sharp RR, Storch EA, Tavares MEA, Tietz GE, Torres-Hernández BA, Tovo-Rodrigues L, Trelles P, Trujillo-ChiVacuan EM, Velásquez MM, Vera-Urbina F, Voloudakis G, Wegman-Ostrosky T, Zhen-Duan J, Zhou H; Latin American Genomics Consortium; Santoro ML, Nicolini H, Atkinson EG, Giusti-Rodríguez P, Montalvo-Ortiz JL.

Nat Genet. 2025 Apr 2. doi: 10.1038/s41588-025-02127-z. Online ahead of print.

PMID: 40175716

CIB2 function is distinct from that of whirlin in the organization of sterocilia architecture.

Giese APJ, Parker A, Rehman S, Brown SDM, Riazuddin S, Vander Kooi CW, Bowl MR, Ahmed ZM.

Dis Model Mech. 2025 Mar 1;18(3):dmm052043. doi: 10.1242/dmm.052043. Epub 2025 Apr 3.

PMID: 40083274

Efficacy of a Novel BCL-xL Degrader, DT2216, in Preclinical Models of JAK2-mutated Post-MPN AML.

Wang Z, Skwarska A, Poigaialwar G, Chaudhry S, Rodriguez-Meira A, Sui P, Olivier E, Jia Y, Gupta V, Fiskus W, Ramage CL, Zheng G, Schurer A, Gritsman K, Papapetrou EP, Bhalla KN, Zhou D, Mead AJ, Rampal RK, Tyner JW, Abbas HA, Pemmaraju N, Tatarata QZ, Konopleva MY.

Blood. 2025 Mar 31:blood.2024027117. doi: 10.1182/blood.2024027117. Online ahead of print.

PMID: 40163809