UFGI Publication Round-up: Week of 5/31/21

How to Transition from Single-Gene Pharmacogenetic Testing to Preemptive Panel-Based Testing: A Tutorial.

Marrero RJ, Cicali EJ, Arwood MJ, Eddy E, DeRemer D, Ramnaraign BH, Daily KC, Jones D Jr, Cook KJ, Cavallari LH, Wiisanen Weitzel K, Langaee T, Newsom KJ, Starostik P, Clare-Salzer MJ, Johnson JA, George TJ, Cooper-DeHoff RM.
Clin Pharmacol Ther. 2020 Sep;108(3):557-565. doi: 10.1002/cpt.1912. Epub 2020 Jul 6.

PMID: 32460360

Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes.

Hiller H, Beachy DE, Lebowitz JJ, Engler S, Mason JR, Miller DR, Kusmarteva I, Jacobsen LM, Posgai AL, Khoshbouei H, Oram RA, Schatz DA, Hattersley AT, Bodenmiller B, Atkinson MA, Nick HS, Wasserfall CH.
Diabetes. 2021 May 25:db210070. doi: 10.2337/db21-0070. Online ahead of print.

PMID: 34035041

Single cell transcriptomic analysis of external genitalia reveals complex and sexually dimorphic cell populations in the early genital tubercle.

Armfield BA, Cohn MJ.
Dev Biol. 2021 May 22:S0012-1606(21)00127-5. doi: 10.1016/j.ydbio.2021.05.014. Online ahead of print.

PMID: 34033822

Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response.

Yu F, Wei J, Cui X, Yu C, Ni W, Bungert J, Wu L, He C, Qian Z.
Nucleic Acids Res. 2021 May 28:gkab415. doi: 10.1093/nar/gkab415. Online ahead of print.

PMID: 34048572

Therapeutic Challenges and Emerging Treatment Targets for Pulmonary Hypertension in Left Heart Disease.

Lteif C, Ataya A, Duarte JD.
J Am Heart Assoc. 2021 May 25:e020633. doi: 10.1161/JAHA.120.020633. Online ahead of print.

PMID: 34032129

Genomics in the Horse Industry: Discovering New Questions at Every Turn.

Brooks SA.
J Equine Vet Sci. 2021 May;100:103456. doi: 10.1016/j.jevs.2021.103456. Epub 2021 Mar 26.

PMID: 34030792

Clostridioides difficile Senses and Hijacks Host Heme for Incorporation into an Oxidative Stress Defense System.

Knippel RJ, Wexler AG, Miller JM, Beavers WN, Weiss A, de Crécy-Lagard V, Edmonds KA, Giedroc DP, Skaar EP.
Cell Host Microbe. 2020 Sep 9;28(3):411-421.e6. doi: 10.1016/j.chom.2020.05.015. Epub 2020 Jun 10.

PMID: 32526159

Sex-Dependent Effects of the Microbiome on Foraging and Locomotion in Drosophila suzukii.

Shu R, Hahn DA, Jurkevitch E, Liburd OE, Yuval B, Wong AC.
Front Microbiol. 2021 May 10;12:656406. doi: 10.3389/fmicb.2021.656406. eCollection 2021.

PMID: 34040592

Mitochondrial and transcriptome responses following exposure to the insecticide fipronil on rat dopaminergic neural cells.

Souders CL 2nd, Rushin A, Sanchez CL, Toth D, Adamovsky O, Martyniuk CJ.
Neurotoxicology. 2021 May 24:S0161-813X(21)00056-5. doi: 10.1016/j.neuro.2021.05.011. Online ahead of print.

PMID: 34044035

Metabolic profiling in human SH-SY5Y neuronal cells exposed to perfluorooctanoic acid (PFOA).

Souders CL 2nd, Sanchez CL, Malphurs W, Aristizabal-Henao JJ, Bowden JA, Martyniuk CJ.
Neurotoxicology. 2021 May 21:S0161-813X(21)00054-1. doi: 10.1016/j.neuro.2021.05.009. Online ahead of print.

PMID: 34029635

3D genomics across the tree of life reveals condensin II as a determinant of architecture type.

Hoencamp C, Dudchenko O, Elbatsh AMO, Brahmachari S, Raaijmakers JA, van Schaik T, Sedeño Cacciatore Á, Contessoto VG, van Heesbeen RGHP, van den Broek B, Mhaskar AN, Teunissen H, St Hilaire BG, Weisz D, Omer AD, Pham M, Colaric Z, Yang Z, Rao SSP, Mitra N, Lui C, Yao W, Khan R, Moroz LL, Kohn A, St Leger J, Mena A, Holcroft K, Gambetta MC, Lim F, Farley E, Stein N, Haddad A, Chauss D, Mutlu AS, Wang MC, Young ND, Hildebrandt E, Cheng HH, Knight CJ, Burnham TLU, Hovel KA, Beel AJ, Mattei PJ, Kornberg RD, Warren WC, Cary G, Gómez-Skarmeta JL, Hinman V, Lindblad-Toh K, Di Palma F, Maeshima K, Multani AS, Pathak S, Nel-Themaat L, Behringer RR, Kaur P, Medema RH, van Steensel B, de Wit E, Onuchic JN, Di Pierro M, Lieberman Aiden E, Rowland BD.
Science. 2021 May 28;372(6545):984-989. doi: 10.1126/science.abe2218.

PMID: 34045355

Organochlorine Pesticide Dieldrin Suppresses Cellular Interferon-related Antiviral Gene Expression.

Russo M, Humes ST, Figueroa AM, Tagmount A, Zhang P, Loguinov A, Lednicky JA, Sabo-Attwood T, Vulpe CD, Liu B.
Toxicol Sci. 2021 May 29:kfab064. doi: 10.1093/toxsci/kfab064. Online ahead of print.

PMID: 34051100

Sobh A, Russo M, Vulpe CD.
Curr Protoc. 2021 May;1(5):e136. doi: 10.1002/cpz1.136.

PMID: 34043288

Characterization of the direct pathway in Dyt1 ΔGAG heterozygous knock-in mice and dopamine receptor 1-expressing-cell-specific Dyt1 conditional knockout mice.

Yokoi F, Chen HX, Oleas J, Dang MT, Xing H, Dexter KM, Li Y.
Behav Brain Res. 2021 May 23:113381. doi: 10.1016/j.bbr.2021.113381. Online ahead of print.

PMID: 34038798

Cecal Slurry Injection in Neonatal and Adult Mice.

Rincon JC, Efron PA, Moldawer LL, Larson SD.
Methods Mol Biol. 2021;2321:27-41. doi: 10.1007/978-1-0716-1488-4_4.

PMID: 34048005

Effects of altered tau expression on dentate granule cell excitability in mice.

Cloyd RA, Koren J 3rd, Abisambra JF, Smith BN.
Exp Neurol. 2021 May 21:113766. doi: 10.1016/j.expneurol.2021.113766. Online ahead of print.

PMID: 34029610

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