UFGI Publication Round-up: Week of 5/24/21

Characterization of an intermolecular quaternary interaction between discrete segments of the Streptococcus mutans adhesin P1 by NMR spectroscopy.

Rivière G, Peng EQ, Brotgandel A, Andring JT, Lakshmanan RV, Agbandje-McKenna M, McKenna R, Brady LJ, Long JR.
FEBS J. 2020 Jun;287(12):2597-2611. doi: 10.1111/febs.15158. Epub 2019 Dec 17.

PMID: 31782893

Corneal Application of R9-SOCS1-KIR Peptide Alleviates Endotoxin-Induced Uveitis.

Ahmed CM, Patel AP, Ildefonso CJ, Johnson HM, Lewin AS.
Transl Vis Sci Technol. 2021 Mar 1;10(3):25. doi: 10.1167/tvst.10.3.25.

PMID: 34003962

The diversification and lineage-specific expansion of nitric oxide signaling in Placozoa: insights in the evolution of gaseous transmission.

Moroz LL, Romanova DY, Nikitin MA, Sohn D, Kohn AB, Neveu E, Varoqueaux F, Fasshauer D.
Sci Rep. 2020 Aug 3;10(1):13020. doi: 10.1038/s41598-020-69851-w.

PMID: 32747709

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.

Mullins N, Forstner AJ, O’Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, Kamitaki N, Kim M, Krebs K, Panagiotaropoulou G, Schilder BM, Sloofman LG, Steinberg S, Trubetskoy V, Winsvold BS, Won HH, Abramova L, Adorjan K, Agerbo E, Al Eissa M, Albani D, Alliey-Rodriguez N, Anjorin A, Antilla V, Antoniou A, Awasthi S, Baek JH, Bækvad-Hansen M, Bass N, Bauer M, Beins EC, Bergen SE, Birner A, Bøcker Pedersen C, Bøen E, Boks MP, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cairns M, Casas M, Cervantes P, Clarke TK, Cruceanu C, Cuellar-Barboza A, Cunningham J, Curtis D, Czerski PM, Dale AM, Dalkner N, David FS, Degenhardt F, Djurovic S, Dobbyn AL, Douzenis A, Elvsåshagen T, Escott-Price V, Ferrier IN, Fiorentino A, Foroud TM, Forty L, Frank J, Frei O, Freimer NB, Frisén L, Gade K, Garnham J, Gelernter J, Giørtz Pedersen M, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha K, Haraldsson M, Hautzinger M, Heilbronner U, Hellgren D, Herms S, Hoffmann P, Holmans PA, Huckins L, Jamain S, Johnson JS, Kalman JL, Kamatani Y, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koromina M, Kranz TM, Kranzler HR, Kubo M, Kupka R, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Lee PH, Levy SE, Lewis C, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Magnusson SH, Maier W, Maihofer A, Malaspina D, Maratou E, Martinsson L, Mattheisen M, McCarroll SA, McGregor NW, McGuffin P, McKay JD, Medeiros H, Medland SE, Millischer V, Montgomery GW, Moran JL, Morris DW, Mühleisen TW, O’Brien N, O’Donovan C, Olde Loohuis LM, Oruc L, Papiol S, Pardiñas AF, Perry A, Pfennig A, Porichi E, Potash JB, Quested D, Raj T, Rapaport MH, DePaulo JR, Regeer EJ, Rice JP, Rivas F, Rivera M, Roth J, Roussos P, Ruderfer DM, Sánchez-Mora C, Schulte EC, Senner F, Sharp S, Shilling PD, Sigurdsson E, Sirignano L, Slaney C, Smeland OB, Smith DJ, Sobell JL, Søholm Hansen C, Soler Artigas M, Spijker AT, Stein DJ, Strauss JS, Świątkowska B, Terao C, Thorgeirsson TE, Toma C, Tooney P, Tsermpini EE, Vawter MP, Vedder H, Walters JTR, Witt SH, Xi S, Xu W, Yang JMK, Young AH, Young H, Zandi PP, Zhou H, Zillich L; HUNT All-In Psychiatry, Adolfsson R, Agartz I, Alda M, Alfredsson L, Babadjanova G, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Blackwood DHR, Boehnke M, Børglum AD, Breen G, Carr VJ, Catts S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Esko T, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens F, Hillert J, Hong KS, Hougaard DM, Hultman CM, Hveem K, Iwata N, Jablensky AV, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kirov G, Landén M, Leboyer M, Lewis CM, Li QS, Lissowska J, Lochner C, Loughland C, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Michie P, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, Mowry B, Müller-Myhsok B, Myers RM, Neale BM, Nievergelt CM, Nordentoft M, Nöthen MM, O’Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato C, Pato MT, Patrinos GP, Perlis RH, Posthuma D, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Ripke S, Rouleau GA, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Shannon Weickert C, Smoller JW, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert TW, Werge T, Wray NR, Zwart JA, Biernacka JM, Nurnberger JI, Cichon S, Edenberg HJ, Stahl EA, McQuillin A, Di Florio A, Ophoff RA, Andreassen OA.
Nat Genet. 2021 May 17. doi: 10.1038/s41588-021-00857-4. Online ahead of print.

PMID: 34002096

Spatial phylogenetics of butterflies in relation to environmental drivers and angiosperm diversity across North America.

Earl C, Belitz MW, Laffan SW, Barve V, Barve N, Soltis DE, Allen JM, Soltis PS, Mishler BD, Kawahara AY, Guralnick R.
iScience. 2021 Mar 23;24(4):102239. doi: 10.1016/j.isci.2021.102239. eCollection 2021 Apr 23.

PMID: 33997666

Asparagine Synthetase Is Highly Expressed at Baseline in the Pancreas Through Heightened PERK Signaling.

Mukherjee A, Ahmed N, Rose FT, Ahmad AN, Javed TA, Wen L, Bottino R, Xiao X, Kilberg MS, Husain SZ.
Cell Mol Gastroenterol Hepatol. 2020;9(1):1-13. doi: 10.1016/j.jcmgh.2019.08.003. Epub 2019 Aug 14.

PMID: 31421261

A Toxic RNA Catalyzes the Cellular Synthesis of Its Own Inhibitor, Shunting It to Endogenous Decay Pathways.

Benhamou RI, Angelbello AJ, Wang ET, Disney MD.
Cell Chem Biol. 2020 Feb 20;27(2):223-231.e4. doi: 10.1016/j.chembiol.2020.01.003. Epub 2020 Jan 24.

PMID: 31981476

Respiratory function during enzyme replacement therapy in late-onset Pompe disease: longitudinal course, prognostic factors, and the impact of time from diagnosis to treatment start.

Stockton DW, Kishnani P, van der Ploeg A, Llerena J Jr, Boentert M, Roberts M, Byrne BJ, Araujo R, Maruti SS, Thibault N, Verhulst K, Berger KI.
J Neurol. 2020 Oct;267(10):3038-3053. doi: 10.1007/s00415-020-09936-8. Epub 2020 Jun 10.

PMID: 32524257

Genomic Characterization of the Fruity Aroma Gene, FaFAD1, Reveals a Gene Dosage Effect on γ-Decalactone Production in Strawberry (Fragaria × ananassa).

Oh Y, Barbey CR, Chandra S, Bai J, Fan Z, Plotto A, Pillet J, Folta KM, Whitaker VM, Lee S.
Front Plant Sci. 2021 May 4;12:639345. doi: 10.3389/fpls.2021.639345. eCollection 2021.

PMID: 34017348

Gene editing isn’t just about food: comments from U.S. focus groups.

McFadden BR, Rumble JN, Stofer KA, Folta KM, Turner S, Pollack A.
GM Crops Food. 2021 May 20:1-11. doi: 10.1080/21645698.2021.1919485. Online ahead of print.

PMID: 34014805

Molecular, functional, and pathological aspects of TDP-43 fragmentation.

Chhangani D, Martín-Peña A, Rincon-Limas DE.
iScience. 2021 Apr 21;24(5):102459. doi: 10.1016/j.isci.2021.102459. eCollection 2021 May 21.

PMID: 34013172

Lactate Dehydrogenase B and Pyruvate Oxidation Pathway Associated With Carfilzomib-Related Cardiotoxicity in Multiple Myeloma Patients: Result of a Multi-Omics Integrative Analysis.

Tantawy M, Chekka LM, Huang Y, Garrett TJ, Singh S, Shah CP, Cornell RF, Baz RC, Fradley MG, Waheed N, DeRemer DL, Yuan L, Langaee T, March K, Pepine CJ, Moreb JS, Gong Y.
Front Cardiovasc Med. 2021 Apr 29;8:645122. doi: 10.3389/fcvm.2021.645122. eCollection 2021.

PMID: 33996940

Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes.

Beam CA, Beli E, Wasserfall CH, Woerner SE, Legge MT, Evans-Molina C, McGrail KM, Silk R, Grant MB, Atkinson MA, DiMeglio LA.
Diabetologia. 2021 May 18. doi: 10.1007/s00125-021-05468-6. Online ahead of print.

PMID: 34003304

OPRM1, OPRK1, and COMT genetic polymorphisms associated with opioid effects on experimental pain: a randomized, double-blind, placebo-controlled study.

Ho KWD, Wallace MR, Staud R, Fillingim RB.
Pharmacogenomics J. 2020 Jun;20(3):471-481. doi: 10.1038/s41397-019-0131-z. Epub 2019 Dec 6.

PMID: 31806881

Low mutation burden and frequent loss of CDKN2A/B and SMARCA2, but not PRC2, define premalignant neurofibromatosis type 1-associated atypical neurofibromas.

Pemov A, Hansen NF, Sindiri S, Patidar R, Higham CS, Dombi E, Miettinen MM, Fetsch P, Brems H, Chandrasekharappa SC, Jones K, Zhu B, Wei JS; National Intramural Sequencing Center (NISC) Comparative Sequencing Program; National Cancer Institute (NCI) Division of Cancer Epidemiology and Genetics (DCEG) Cancer Genomics Research Laboratory, Mullikin JC, Wallace MR, Khan J, Legius E, Widemann BC, Stewart DR.
Neuro Oncol. 2019 Aug 5;21(8):981-992. doi: 10.1093/neuonc/noz028.

PMID: 30722027

Reflections of Healthcare Experiences of African Americans With Sickle Cell Disease or Cancer: A Qualitative Study.

Dyal BW, Abudawood K, Schoppee TM, Jean S, Smith VM, Greenlee A, Staton LM, Duckworth L, Mandernach MW, Black V, Heldermon CD, Yao Y, Wilkie DJ, Ezenwa MO.
Cancer Nurs. 2021 Jan/Feb;44(1):E53-E61. doi: 10.1097/NCC.0000000000000750.

PMID: 31743153

Alterations in mouse spinal cord and sciatic nerve microRNAs after the chronic constriction injury (CCI) model of neuropathic pain.

Wilkerson JL, Jiang J, Felix JS, Bray JK, da Silva L, Gharaibeh RZ, McMahon LR, Schmittgen TD.
Neurosci Lett. 2020 Jul 13;731:135029. doi: 10.1016/j.neulet.2020.135029. Epub 2020 May 5.

PMID: 32380144

Axially Chiral Cannabinols: A New Platform for Cannabinoid-Inspired Drug Discovery.

Navaratne PV, Wilkerson JL, Ranasinghe KD, Semenova E, Felix JS, Ghiviriga I, Roitberg A, McMahon LR, Grenning AJ.
ChemMedChem. 2020 May 6;15(9):728-732. doi: 10.1002/cmdc.202000025. Epub 2020 Mar 16.

PMID: 32061146

Skin-Related complications of Klippel-Trenaunay Syndrome: a retrospective review of 410 patients.

Anderson KR, Nguyen H, Schoch JJ, Lohse CM, Driscoll DJ, Tollefson MM.
J Eur Acad Dermatol Venereol. 2021 Feb;35(2):517-522. doi: 10.1111/jdv.16999. Epub 2020 Dec 5.

PMID: 33070382

Radiation Treatment, ATM, BRCA1/2, and CHEK2*1100delC Pathogenic Variants and Risk of Contralateral Breast Cancer.

Reiner AS, Robson ME, Mellemkjær L, Tischkowitz M, John EM, Lynch CF, Brooks JD, Boice JD, Knight JA, Teraoka SN, Liang X, Woods M, Shen R, Shore RE, Stram DO, Thomas DC, Malone KE, Bernstein L, Riaz N, Woodward W, Powell S, Goldgar D, Concannon P; WECARE Study Collaborative Group, Bernstein JL.
J Natl Cancer Inst. 2020 Dec 14;112(12):1275-1279. doi: 10.1093/jnci/djaa031.

PMID: 32119081

Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers.

Houser MC, Mac V, Smith DJ, Chicas RC, Xiuhtecutli N, Flocks JD, Elon L, Tansey MG, Sands JM, McCauley L, Hertzberg VS.
Biol Res Nurs. 2021 May 21:10998004211016070. doi: 10.1177/10998004211016070. Online ahead of print.

PMID: 34018403

Genomewide Association Studies of LRRK2 Modifiers of Parkinson’s Disease.

Lai D, Alipanahi B, Fontanillas P, Schwantes-An TH, Aasly J, Alcalay RN, Beecham GW, Berg D, Bressman S, Brice A, Brockman K, Clark L, Cookson M, Das S, Van Deerlin V, Follett J, Farrer MJ, Trinh J, Gasser T, Goldwurm S, Gustavsson E, Klein C, Lang AE, Langston JW, Latourelle J, Lynch T, Marder K, Marras C, Martin ER, McLean CY, Mejia-Santana H, Molho E, Myers RH, Nuytemans K, Ozelius L, Payami H, Raymond D, Rogaeva E, Rogers MP, Ross OA, Samii A, Saunders-Pullman R, Schüle B, Schulte C, Scott WK, Tanner C, Tolosa E, Tomkins JE, Vilas D, Trojanowski JQ; 23andMe Research Team, Uitti R, Vance JM, Visanji NP, Wszolek ZK, Zabetian CP, Mirelman A, Giladi N, Orr Urtreger A, Cannon P, Fiske B, Foroud T.
Ann Neurol. 2021 May 2. doi: 10.1002/ana.26094. Online ahead of print.

PMID: 33938021

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