UFGI Publication round-up week 10/1

Ataluren in patients with nonsense mutation Duchenne muscular dystrophy (ACT DMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.

McDonald CM, Campbell C, Torricelli RE, Finkel RS, Flanigan KM, Goemans N, Heydemann P, Kaminska A, Kirschner J, Muntoni F, Osorio AN, Schara U, Sejersen T, Shieh PB, Sweeney HL, Topaloglu H, Tulinius M, Vilchez JJ, Voit T, Wong B, Elfring G, Kroger H, Luo X, McIntosh J, Ong T, Riebling P, Souza M, Spiegel RJ, Peltz SW, Mercuri E; Clinical Evaluator Training Group; ACT DMD Study Group.

Lancet. 2017 Sep 23;390(10101):1489-1498. doi: 10.1016/S0140-6736(17)31611-2. Epub 2017 Jul 17.

PMID: 28728956

 

Surveying the genome and constructing a high-density genetic map of napiergrass (Cenchrus purpureus Schumach).

Paudel D, Kannan B, Yang X, Harris-Shultz K, Thudi M, Varshney RK, Altpeter F, Wang J.

Sci Rep. 2018 Sep 26;8(1):14419. doi: 10.1038/s41598-018-32674-x.

PMID: 30258215

 

Stimulation of AMPK prevents degeneration of photoreceptors and the retinal pigment epithelium.

Xu L, Kong L, Wang J, Ash JD.

Proc Natl Acad Sci U S A. 2018 Sep 24. pii: 201802724. doi: 10.1073/pnas.1802724115.

PMID: 30249643

 

Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy.

 

Sayour EJ, Grippin A, De Leon G, Stover B, Rahman M, Karachi A, Wummer B, Moore G, Castillo-Caro P, Fredenburg K, Sarkisian MR, Huang J, Deleyrolle LP, Sahay B, Carrera-Justiz S, Mendez-Gomez HR, Mitchell DA. Nano Lett. 2018 Sep 27. doi: 10.1021/acs.nanolett.8b02179.

PMID: 30259750

 

Global role of the bacterial post-transcriptional regulator CsrA revealed by integrated transcriptomics.

Potts AH, Vakulskas CA, Pannuri A, Yakhnin H, Babitzke P, Romeo T.

Nat Commun. 2017 Nov 17;8(1):1596. doi: 10.1038/s41467-017-01613-1.

PMID: 29150605

 

Mouse Gamma Herpesvirus MHV-68 Induces Severe Gastrointestinal (GI) Dilatation in Interferon Gamma Receptor-Deficient Mice (IFNγR-/-) That Is Blocked by Interleukin-10.

Chen H, Bartee MY, Yaron JR, Liu L, Zhang L, Zheng D, Hogue IB, Bullard WL, Tibbetts S, Lucas AR.

Viruses. 2018 Sep 23;10(10). pii: E518. doi: 10.3390/v10100518.

PMID: 30249047

 

A mouse model of angelman syndrome imprinting defects.

Lewis MW, Vargas-Franco D, Morse DA, Resnick JL.

Hum Mol Genet. 2018 Sep 26. doi: 10.1093/hmg/ddy345. [Epub ahead of print]

PMID: 30260400

 

De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.

Wang S, Mandell JD, Kumar Y, Sun N, Morris MT, Arbelaez J, Nasello C, Dong S, Duhn C, Zhao X, Yang Z, Padmanabhuni SS, Yu D, King RA, Dietrich A, Khalifa N, Dahl N, Huang AY, Neale BM, Coppola G, Mathews CA, Scharf JM; Tourette International Collaborative Genetics Study (TIC Genetics); Tourette Syndrome Genetics Southern and Eastern Europe Initiative (TSGENESEE); Tourette Association of America International Consortium for Genetics (TAAICG), Fernandez TV, Buxbaum JD, De Rubeis S, Grice DE, Xing J, Heiman GA, Tischfield JA, Paschou P, Willsey AJ, State MW.

Cell Rep. 2018 Sep 25;24(13):3441-3454.e12. doi: 10.1016/j.celrep.2018.08.082.

PMID: 30257206

 

Novel biomarker signatures for idiopathic REM sleep behavior disorder: A proteomic and system biology approach.

Mondello S, Kobeissy F, Mechref Y, Zhao J, Talih FR, Cosentino F, Antelmi E, Moresco M, Plazzi G, Ferri R.

Neurology. 2018 Sep 26. pii: 10.1212/WNL.0000000000006439. doi: 10.1212/WNL.0000000000006439.

PMID: 30258025

 

Evolutionary insights from comparative transcriptome and transcriptome-wide coalescence analyses in Tetrastigma hemsleyanum.

Wang Y, Jiang W, Ye W, Fu C, Gitzendanner MA, Soltis PS, Soltis DE, Qiu Y.

BMC Plant Biol. 2018 Sep 24;18(1):208. doi: 10.1186/s12870-018-1429-8.

PMID: 30249188

 

Developmental toxicity of the fungicide ziram in zebrafish (Danio rerio).

Cao F, Souders CL 2nd, Li P, Adamovsky O, Pang S, Qiu L, Martyniuk CJ.

Chemosphere. 2018 Sep 19;214:303-313. doi: 10.1016/j.chemosphere.2018.09.105.

PMID: 30265938

 

Age-Structured Population Modeling of HPV-related Cervical Cancer in Texas and US.

Peng HL, Tam S, Xu L, Dahlstrom KR, Wu CF, Fu S, Zhong C, Chan W, Sturgis EM, Ramondetta L, Rong L, Lairson DR, Miao H.

Sci Rep. 2018 Sep 25;8(1):14346. doi: 10.1038/s41598-018-32566-0.

PMID: 30254252

 

Gene expression profile and molecular pathway datasets resulting from benzo(a)pyrene exposure in the liver and testis of adult tilapia.

Colli-Dula RC, Fang X, Moraga-Amador D, Albornoz-Abud N, Zamora-Bustillos R, Conesa A, Zapata-Perez O, Moreno D, Hernandez-Nuñez E.

Data Brief. 2018 Sep 5;20:1500-1509. doi: 10.1016/j.dib.2018.08.206. eCollection 2018 Oct.

PMID: 30258954

 

Independent and Joint-GWAS for growth traits in Eucalyptus by assembling genome-wide data for 3373 individuals across four breeding populations.

Müller BSF, de Almeida Filho JE, Lima BM, Garcia CC, Missiaggia A, Aguiar AM, Takahashi E, Kirst M, Gezan SA, Silva-Junior OB, Neves LG, Grattapaglia D.

New Phytol. 2018 Sep 25. doi: 10.1111/nph.15449.

PMID: 30252143

 

In-grove spatio-temporal spread of citrus huanglongbing and its psyllid vector in relation to weather.

Shimwela M, Halbert SE, Manjunath KL, Mears P, Singer B, Lee WS, Jones JB, Ploetz R, van Bruggen AHC.

Phytopathology. 2018 Sep 26. doi: 10.1094/PHYTO-03-18-0089-R.

PMID: 30256188

 

Developmental, genetic, and genomic insights into the evolutionary loss of limbs in snakes.

Leal F, Cohn MJ.

Genesis. 2018 Jan;56(1). doi: 10.1002/dvg.23077. Epub 2017 Nov 2. Review.

PMID: 29095557

 

Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress.

Biswal MR, Justis BD, Han P, Li H, Gierhart D, Dorey CK, Lewin AS.

PLoS One. 2018 Sep 28;13(9):e0203816. doi: 10.1371/journal.pone.0203816. eCollection 2018.

PMID: 30265681

 

Periorbital and Temporal Anatomy, “Targeted Fat Grafting,” and How a Novel Circulatory System in Human Peripheral Nerves and Brain May Help Avoid Nerve Injury and Blindness During Routine Facial Augmentation.

Pessa JE, Kenkel JM, Heldermon CD.

Aesthet Surg J. 2017 Sep 1;37(8):969-973. doi: 10.1093/asj/sjx089. No abstract available.

PMID: 28595323

 

Surveying the genome and constructing a high-density genetic map of napiergrass (Cenchrus purpureus Schumach).

Paudel D, Kannan B, Yang X, Harris-Shultz K, Thudi M, Varshney RK, Altpeter F, Wang J.

Sci Rep. 2018 Sep 26;8(1):14419. doi: 10.1038/s41598-018-32674-x.

PMID: 30258215

 

Geriatric traumatic brain injury-What we know and what we don’t.

Stein DM, Kozar RA, Livingston DH, Luchette F, Adams SD, Agrawal V, Arbabi S, Ballou J, Barraco RD, Bernard AC, Biffl WL, Bosarge PL, Brasel KJ, Cooper Z, Efron PA, Fakhry SM, Hartline CA, Hwang F, Joseph BA, Kurek SJ, Moore FA, Mosenthal AC, Pathak AS, Truitt MS, Yelon JA; AAST Geriatric Trauma/ACS Committee.

J Trauma Acute Care Surg. 2018 Oct;85(4):788-798. doi: 10.1097/TA.0000000000001910. No abstract available.

PMID: 30256343

 

The Role of Accessory Cells in Islet Homeostasis.

Tang SC, Jessup CF, Campbell-Thompson M.

Curr Diab Rep. 2018 Sep 28;18(11):117. doi: 10.1007/s11892-018-1096-z. Review.

PMID: 30267158

 

Enhanced in vitro activity of tigecycline in the presence of chelating agents.

Deitchman AN, Singh RSP, Rand KH, Derendorf H.

Int J Antimicrob Agents. 2018 May;51(5):799-802. doi: 10.1016/j.ijantimicag.2017.12.027. Epub 2018 Jan 3.

PMID: 29305959

 

Independent and Joint-GWAS for growth traits in Eucalyptus by assembling genome-wide data for 3373 individuals across four breeding populations.

Müller BSF, de Almeida Filho JE, Lima BM, Garcia CC, Missiaggia A, Aguiar AM, Takahashi E, Kirst M, Gezan SA, Silva-Junior OB, Neves LG, Grattapaglia D.

New Phytol. 2018 Sep 25. doi: 10.1111/nph.15449.

PMID: 30252143

 

 

Newly-discovered enzymes that function in metabolite damage-control.

de Crécy-Lagard V, Haas D, Hanson AD.

Curr Opin Chem Biol. 2018 Sep 27;47:101-108. doi: 10.1016/j.cbpa.2018.09.014. Review.

PMID: 30268903