UFGI Publication Round-up: Week 7/27/20

Low-dose triptolide enhances antitumor effect of JQ1 on acute myeloid leukemia through inhibiting RNA polymerase II in vitro and in vivo.

Shi Y, Zhao H, Ye J, Li Z, Deng M, Zha J, Zhou Y, Zeng H, Lin Y, Pu X, Guo C, Song H, Qiu Y, Xu B.

Mol Carcinog. 2020 Jul 21. doi: 10.1002/mc.23238. Online ahead of print.

PMID: 32691884

Risk Factors for Recurrent Staphylococcus aureus Bacteremia.

Choi SH, Dagher M, Ruffin F, Park LP, Sharma-Kuinkel BK, Souli M, Morse AM, Eichenberger EM, Hale L, Kohler C, Warren B, Hansen B, Medie FM, McIntyre LM, Fowler VG.

Clin Infect Dis. 2020 Jun 21:ciaa801. doi: 10.1093/cid/ciaa801. Online ahead of print.

PMID: 32564065

DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas.

He Y, Koch R, Budamagunta V, Zhang P, Zhang X, Khan S, Thummuri D, Ortiz YT, Zhang X, Lv D, Wiegand JS, Li W, Palmer AC, Zheng G, Weinstock DM, Zhou D.

J Hematol Oncol. 2020 Jul 16;13(1):95. doi: 10.1186/s13045-020-00928-9.

PMID: 32677976

PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics.

Khan S, He Y, Zhang X, Yuan Y, Pu S, Kong Q, Zheng G, Zhou D.

Oncogene. 2020 Jun;39(26):4909-4924. doi: 10.1038/s41388-020-1336-y. Epub 2020 May 31.

PMID: 32475992

Systemic clearance of p16INK4a -positive senescent cells mitigates age-associated intervertebral disc degeneration. 

Patil P, Dong Q, Wang D, Chang J, Wiley C, Demaria M, Lee J, Kang J, Niedernhofer LJ, Robbins PD, Sowa G, Campisi J, Zhou D, Vo N.

Aging Cell. 2019 Jun;18(3):e12927. doi: 10.1111/acel.12927. Epub 2019 Mar 21.

PMID: 30900385

Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice. 

Zu T, Guo S, Bardhi O, Ryskamp DA, Li J, Khoramian Tusi S, Engelbrecht A, Klippel K, Chakrabarty P, Nguyen L, Golde TE, Sonenberg N, Ranum LPW.

Proc Natl Acad Sci U S A. 2020 Jul 20:202005748. doi: 10.1073/pnas.2005748117. Online ahead of print.

PMID: 32690681

Differential response to targeted acupuncture by gender in patients with gastrointestinal cancer cachexia: secondary analysis of a randomized controlled trial. 

Yoon SL, Grundmann O, Williams JJ, Wu SS, Leeuwenburgh C, Huo Z, George TJ Jr.

Acupunct Med. 2020 Feb;38(1):53-60. doi: 10.1177/0964528419873670. Epub 2019 Sep 23.

PMID: 31544469

Patient and physician perceptions about blood transfusions in the myelodysplastic syndromes. 

King D, Schmidt R, Lesser M, Houk A, Salkeld E, Cogle CR.

Leuk Res. 2020 Jul 15;96:106425. doi: 10.1016/j.leukres.2020.106425. Online ahead of print.

PMID: 32702549

Time-of-day dependent effects of contractile activity on the phase of the skeletal muscle clock. 

Kemler D, Wolff CA, Esser KA.

J Physiol. 2020 Jun 14. doi: 10.1113/JP279779. Online ahead of print.

PMID: 32537739

Impact of white-spotting alleles, including W20, on phenotype in the American Paint Horse. 

Brooks SA, Palermo KM, Kahn A, Hein J.

Anim Genet. 2020 Jul 20. doi: 10.1111/age.12960. Online ahead of print.

PMID: 32686191

Developmental and regenerative paradigms of cilia regulated hedgehog signaling. 

Kopinke D, Norris AM, Mukhopadhyay S.

Semin Cell Dev Biol. 2020 Jun 12:S1084-9521(19)30163-6. doi: 10.1016/j.semcdb.2020.05.029. Online ahead of print.

PMID: 32540122

Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. 

Laffranchi M, Elliston EL, Miranda E, Perez J, Ronzoni R, Jagger AM, Heyer-Chauhan N, Brantly ML, Fra A, Lomas DA, Irving JA.

JCI Insight. 2020 Jul 23;5(14):135459. doi: 10.1172/jci.insight.135459.

PMID: 32699193

Disease in Invasive Plant Populations. 

Goss EM, Kendig AE, Adhikari A, Lane B, Kortessis N, Holt RD, Clay K, Harmon PF, Luke Flory S.

Annu Rev Phytopathol. 2020 Jun 9. doi: 10.1146/annurev-phyto-010820-012757. Online ahead of print.

PMID: 32516034

Spatially propagating activation of quorum sensing in Vibrio fischeri and the transition to low population density. 

Patel K, Rodriguez C, Stabb EV, Hagen SJ.

Phys Rev E. 2020 Jun;101(6-1):062421. doi: 10.1103/PhysRevE.101.062421.

PMID: 32688581

Pharmacokinetics and Safety of Mitragynine in Beagle Dogs. 

Maxwell EA, King TI, Kamble SH, Raju KSR, Berthold EC, León F, Avery BA, McMahon LR, McCurdy CR, Sharma A.

Planta Med. 2020 Jul 21. doi: 10.1055/a-1212-5475. Online ahead of print.

PMID: 32693425

Experiences of Discrimination Are Associated With Worse Metabolic Syndrome Severity Among African Americans in the Jackson Heart Study. 

Cardel MI, Chi X, Min YI, Sims M, Musani SK, Dulin A, Gravlee CC, Smith SM, DeBoer MD, Gurka MJ.

Ann Behav Med. 2020 Jul 20:kaaa050. doi: 10.1093/abm/kaaa050. Online ahead of print.

PMID: 32686818

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