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Early exposure to excess hormone causes genital defects in females

University of Florida researchers have identified cells targeted by a male hormone and found that an excess of that hormone at a specific time can cause genital defects in female mice. The findings appear today (Nov. 7) in the Proceedings of the National Academy of Sciences. The...
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UFGI Publications Round-Up Week 10/31/2016

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Author information: Babon JA1, DeNicola ME1, Blodgett DM1, Crèvecoeur I2, Buttrick TS3, Maehr R4, Bottino R5,6, Naji A7, Kaddis J8, Elyaman W3, James EA9, Haliyur R10,...
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UFGI researcher immortalizes NF1 neurofibroma Schwann cells

Although tumors are typically best-known for their capacity to grow quickly, not all of them are so robust. This limited life span creates challenges for scientists attempting to research them. A University of Florida research team recently discovered a method for boosting the...
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UFGI Publications Round-Up Week 10/26/2016

The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK. Author information: Wu CW1, Deonarine A2, Przybysz A3, Strange K4, Choe KP1. 1Department of Biology and Genetics Institute, University of...
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UF Health: UF Genetics Institute researchers find genetic change that caused snakes to lose legs

  About 150 million years ago, snakes roamed about on well-developed legs. Now, two University of Florida researchers have discovered how snakes’ legs eventually disappeared. Snakes lost their legs due to a trio of mutations in a genetic switch — known as an enhancer — that...
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Biology researcher discovers new role for jasmonic acid in plants

  A research team led by University of Florida Genetics Institute member Sixue Chen, PhD, recently discovered a new role for jasmonic acid in plants. Scientists have long been aware of the existence of jasmonic acid, and its role associated with defense from predators....
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UFGI Publications Round-Up Week 10/17

Genomic Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit. Author information: Azarian T1,2, Maraqa NF3,4, Cook RL1,2, Johnson JA2,5, Bailey C3, Wheeler S3, Nolan D2,5, Rathore MH3,4, Morris JG Jr2,6, Salemi M2,5. 1College of Public...
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UFGI Publications Round-Up Week 10/10/2016

Identification of large disjoint motifs in biological networks. Author information: Elhesha R1, Kahveci T2. 1CISE Department, University of Florida, 432 Newell Dr, Gainesville, Florida, 32611, USA. relhesha@cise.ufl.edu. 2CISE Department, University of Florida, 432 Newell Dr,...
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UF Health– UF Genetics Institute member contributes to novel Alzheimer’s discovery

Two University of Florida Health researchers have made a discovery that could provide a novel way to target the brain deterioration associated with amyloid plaque build-up in Alzheimer’s disease. Diego Rincon-Limas, Ph.D., an assistant professor in the department of neurology and...
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UFGI Publications Round-Up Week 10/03/2016

Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes. Author information: Chang SW1, McDonough CW1, Gong Y1, Johnson TA2, Tsunoda T2,3, Gamazon ER4, Perera MA5, Takahashi A6, Tanaka T7, Kubo M8,...
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